http://news.bbc.co.uk/1/hi/health/3900679.stm




Last Updated: Friday, 16 July, 2004, 23:26 GMT 00:26 UK


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Healthy combos ward off cancer

When combined with tomato, broccoli was even more powerful

Eating tomatoes and broccoli together may offer better protection
against cancer than eating either alone, say US researchers.

Both are known to contain cancer-fighting chemicals, but the authors say
when put together, they interact to maximise the effect.

Rats fed both foods together had less prostate cancer growth than rats
fed either tomatoes or broccoli.

Dr John Erdman presented his findings at a US conference on food and
cancer.

Combining foods

Dr Erdman, professor of Food Science and Human Nutrition at the
University of Illinois, said: "We decided to look at these foods in
combination because we believed it was a way to learn more about real
diets eaten by real people.

"People don't eat nutrients, they eat food. And they don't eat one food,
they eat many foods in combination."

His team had previously found rats fed lycopene - the chemical in
tomatoes thought to fight cancer - were not afforded greater protection
against prostate cancer.

But rats fed freeze-dried tomato powder, which contains the full range
of vitamins and nutrients of normal tomatoes, were.

Similarly, the cancer-fighting compounds found in broccoli, called
glucosinolates, have been shown to work better when they act with all of
the other natural substances found in broccoli.


Together, they bring out the best in each other and maximise the
cancer-fighting effect



Lead researcher Dr John Erdman


Dr Erdman's team examined how different food and nutrient combinations
affected the growth of prostate tumours in rats.

Rats that ate a combination of broccoli and tomato powders had less
growth of their tumours than rats who ate either of the two powders
alone and rats given diets supplemented with lycopene.

A final group of rats was fed a normal diet and given a drug commonly
prescribed to men with benign growth of the prostate which is also being
tested for its potential to prevent prostate cancer.

All of the other diets were better at preventing tumour growth than the
drug.

Dr Erdman said: "These preliminary results suggest that there is, in
fact, an interactive protective effect between tomatoes and broccoli.

Cancer-fighting

"Separately, these two foods appear to have enormous cancer-fighting
potential. Together, they bring out the best in each other and maximise
the cancer-fighting effect," he said.

He said other plant food combinations - fruits, vegetables, whole grains
and beans - were likely to have a similar effect.

Dr Emma Knight, Science Information Officer for Cancer Research UK says:
"Experts believe that changes to our diet could help prevent around
one-third of cancers.

"But the link between diet and cancer is complex and it is difficult to
identify the precise components of a food responsible for any protective
effect.

"This research supports previous dietary studies showing that eating a
diet rich in vegetables and fruits protects men from prostate cancer.

"It also backs current thinking that interactions between different
substances in the diet are important and that supplements are not
necessarily effective in preventing cancer.

"The best practical advice remains to increase your intake of a wide
variety of fruits and vegetables, a message that is reinforced by this
study's findings," she said.

Dr Erdman spoke at the International Research Conference on Food,
Nutrition, and Cancer, set up by the American Institute for Cancer
Research and the World Cancer Research Fund International.

His findings will be published in the Journal of Nutrition in December.