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Science Forum Index » Life Extension Forum » Gum arabic establishes prebiotic functionality in...
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| rs1000b at (no spam) yahoo.com... |
 Posted: Sun May 11, 2008 12:23 pm |
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Br J Nutr. 2008 May 9;:1-7 [Epub ahead of print]
Gum arabic establishes prebiotic functionality in healthy human
volunteers in a dose-dependent manner.
Calame W, Weseler AR, Viebke C, Flynn C, Siemensma AD.
Kerry Group Nutrition Technical Center, Veluwezoom 62, 1327 AH Almere,
The Netherlands.
The present study was undertaken to determine the prebiotic efficacy
of gum arabic upon consumption by man for up to 4 weeks and, if any,
to establish the dose-effect relationship. Human healthy volunteers
consumed various daily doses (5, 10, 20, 40 g) of gum arabic
(EmulGold(R)) in water for up to 4 weeks. Daily consumption of water
was taken as the negative control and that of 10 g inulin as the
positive control. At 0, 1, 2 and 4 weeks quantification of bacterial
numbers in stool samples was performed via real time-PCR techniques
and questionnaires were filled in to account for potential drawbacks.
The genera of Bifidobacteria and Lactobacilli were taken as
potentially beneficial bacteria and those of Bacteroides, Clostridium
difficile and Enterococci as potentially non-beneficial, this
distinction was dependent on the issue of these numbers being or
becoming out of balance in the host. Compared with the negative
control the numbers of Bifidobacteria and Lactobacilli 4 weeks after
consumption were significantly higher for gum arabic: the optimal dose
being around 10 g. Moreover, at this dose the numbers of
Bifidobacteria, Lactobacilli and Bacteroides were significantly higher
for gum arabic than for inulin. No significant drawback was
encountered during the study. It is concluded that gum arabic
establishes prebiotic efficacy, at least as good as inulin. The
optimal daily dose was found to be 10 g.
PMID: 18466655 [PubMed - as supplied by publisher] |
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