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Science Forum Index » Immunology Forum » New Proteins Detected On Silicone Breast Implants
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| Ilena Rose |
 Posted: Mon Apr 23, 2007 8:08 pm |
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Brought to you by Ilena Rosenthal and The Humantics Foundation
www.BreastImplantAwareness.org
http://www.medicalnewstoday.com/medicalnews.php?newsid=59293
Scientists in Austria are reporting detection of previously
unrecognized proteins that accumulate on the surface of silicone
breast implants after implants are in the body. Georg Wick and
colleagues say that the proteins may be involved in causing immune
reactions in patients from breast implants and other types of silicone
implants.
Their research involved 23 healthy women who were undergoing breast
augmentation for cosmetic reasons, including some who were removing or
replacing implants due to complications.
In an article in the December issue of ACS' Journal of Proteome
Research, a monthly publication, the scientists describe using a
targeted proteomics approach to identify proteins adsorbed to the
surface of silicone because those proteins have been identified as key
components in local immune reactions to silicone. "Thus far we have
identified the 30 most abundant proteins deposited on the surface of
silicone, the largest known inventory of such proteins so far."
Noting uncertainty about any link between autoimmune disease and
silicone implants, they state that the new report "shows that silicone
promotes at least the adhesion of altered self-proteins, which in turn
may trigger an autoimmune response of the immune system." |
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