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Science Forum Index » Medicine - Cancer Forum » Bloodletting Against Cancer...
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| ironjustice... |
 Posted: Wed Jul 23, 2008 1:52 am |
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| ironjustice... |
| Posted: Wed Jul 23, 2008 1:52 am |
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"These results almost seem to be too good to be true."
Reducing Iron Stores by Phlebotomy Lowers Cancer Risk in Older Men
NEW YORK (Reuters Health) Jul 08 - Cancer incidence and mortality in
older men may be reduced by repeated phlebotomy to lower serum
ferritin levels, according to findings published online on July 8 in
the Journal of the National Cancer Institute.
Observational studies suggest that lower body iron stores may protect
against malignancy by reducing iron-induced oxidative stress, Dr. Leo
R. Zacharski and his associates note.
To test this possibility, Dr. Zacharski, at the White River Junction
Veterans Affairs Medical Center, Vermont, and his group conducted an
ad hoc analysis of data from a VA study in which patients with
peripheral arterial disease were assigned to repeated blood
collections (n = 636) or to a control group (n = 641), originally for
prevention of atherosclerotic complications .
The population was 99% male, mean age 67 years, with mean ferritin
levels at baseline of 122 ng/mL. Phlebotomy was scheduled every 6
months to maintain ferritin levels between 25 and 60 ng/mL. During a
mean follow-up of 4.5 years, there were 60 new visceral malignancies
in the control patients and 38 in the iron-reduction patients (p =
0.023).
The risk of new malignancy (hazard ratio 0.65, p = 0.036) was
significantly lower in the phlebotomy group. Among patients who did
develop cancer, cancer-specific mortality (HR 0.39, p = 0.003) and
all-
cause mortality (HR 0.49, p = 0.009) were lower in the phlebotomy
group.
Overall, 75% of new cancers occurred in patients with mean ferritin
levels > 57 ng/mL.
These findings do not pertain to younger patients without vascular
disease, women, or African Americans, whose ferritin levels are
higher
than those of Caucasians, the investigators say. Instead, "these
observations provide incentive for future studies and insight into
optimal clinical trial design."
Dr. Zacharski's team suggests "there may be a need to redefine the
normal range for the serum ferritin level based on associated disease
risk." They also call for re-evaluation of the policy of routinely
administering iron to anemic cancer patients.
In a related editorial, Dr. Mads Melbye, at Statens Serum Institut in
Copenhagen and colleagues suggest that "these results almost seem to
be too good to be true."
While recommending that "all possibilities for bias must be carefully
examined" and that "the results have to be interpreted with caution,"
the editorialists also support more research on this topic.
Furthermore, they write, "a cautious standpoint toward iron
supplementation where no proper indication exists is perhaps
advisable."
J Natl Cancer Inst 2008;100.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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| ironjustice... |
| Posted: Wed Jul 23, 2008 8:42 am |
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On Jul 23, 8:22 am, J <xnswex at (no spam) nalid;"no> wrote: please keep it on your
own
newsgroup. <<
'J' .. AGAIN .. snipped the cancer groups.
You've been told to stay off my threads .. jwootton ..
"THESE RESULTS ALMOST SEEM TO GOOD TO BE .. TRUE."
Reducing Iron Stores by Phlebotomy Lowers Cancer Risk in Older Men
NEW YORK (Reuters Health) Jul 08 - Cancer incidence and mortality in
older men may be reduced by repeated phlebotomy to lower serum
ferritin levels, according to findings published online on July 8 in
the Journal of the National Cancer Institute.
Observational studies suggest that lower body iron stores may protect
against malignancy by reducing iron-induced oxidative stress, Dr. Leo
R. Zacharski and his associates note.
To test this possibility, Dr. Zacharski, at the White River Junction
Veterans Affairs Medical Center, Vermont, and his group conducted an
ad hoc analysis of data from a VA study in which patients with
peripheral arterial disease were assigned to repeated blood
collections (n = 636) or to a control group (n = 641), originally for
prevention of atherosclerotic complications .
The population was 99% male, mean age 67 years, with mean ferritin
levels at baseline of 122 ng/mL. Phlebotomy was scheduled every 6
months to maintain ferritin levels between 25 and 60 ng/mL. During a
mean follow-up of 4.5 years, there were 60 new visceral malignancies
in the control patients and 38 in the iron-reduction patients (p 0.023).
The risk of new malignancy (hazard ratio 0.65, p = 0.036) was
significantly lower in the phlebotomy group. Among patients who did
develop cancer, cancer-specific mortality (HR 0.39, p = 0.003) and
all-
cause mortality (HR 0.49, p = 0.009) were lower in the phlebotomy
group.
Overall, 75% of new cancers occurred in patients with mean ferritin
levels > 57 ng/mL.
These findings do not pertain to younger patients without vascular
disease, women, or African Americans, whose ferritin levels are
higher
than those of Caucasians, the investigators say. Instead, "these
observations provide incentive for future studies and insight into
optimal clinical trial design."
Dr. Zacharski's team suggests "there may be a need to redefine the
normal range for the serum ferritin level based on associated disease
risk." They also call for re-evaluation of the policy of routinely
administering iron to anemic cancer patients.
In a related editorial, Dr. Mads Melbye, at Statens Serum Institut in
Copenhagen and colleagues suggest that "these results almost seem to
be too good to be true."
While recommending that "all possibilities for bias must be carefully
examined" and that "the results have to be interpreted with caution,"
the editorialists also support more research on this topic.
Furthermore, they write, "a cautious standpoint toward iron
supplementation where no proper indication exists is perhaps
advisable."
J Natl Cancer Inst 2008;100.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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| J... |
| Posted: Wed Jul 23, 2008 10:22 am |
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Guest
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Michael B wrote:
Quote: Don't discourage him from making an actual observation.
He could possibly show us that he can actually review the
available information and make a valid assessment. He would
still have issues with causality, but one thing at a time.
If you're going to continue feeding the troll, please keep it on your own
newsgroup.
J |
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| ironjustice... |
| Posted: Wed Jul 23, 2008 4:00 pm |
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On Jul 23, 3:47 pm, "Cheeky Bastard" <InvalidEm... at (no spam) aol.com> wrote:
testosterone depleted retarded fatboy <<
"THESE RESULTS ALMOST SEEM TOO GOOD TO BE .. TRUE."
Reducing Iron Stores by Phlebotomy Lowers Cancer Risk in Older Men
NEW YORK (Reuters Health) Jul 08 - Cancer incidence and mortality in
older men may be reduced by repeated phlebotomy to lower serum
ferritin levels, according to findings published online on July 8 in
the Journal of the National Cancer Institute.
Observational studies suggest that lower body iron stores may protect
against malignancy by reducing iron-induced oxidative stress, Dr. Leo
R. Zacharski and his associates note.
To test this possibility, Dr. Zacharski, at the White River Junction
Veterans Affairs Medical Center, Vermont, and his group conducted an
ad hoc analysis of data from a VA study in which patients with
peripheral arterial disease were assigned to repeated blood
collections (n = 636) or to a control group (n = 641), originally for
prevention of atherosclerotic complications .
The population was 99% male, mean age 67 years, with mean ferritin
levels at baseline of 122 ng/mL. Phlebotomy was scheduled every 6
months to maintain ferritin levels between 25 and 60 ng/mL. During a
mean follow-up of 4.5 years, there were 60 new visceral malignancies
in the control patients and 38 in the iron-reduction patients (p 0.023).
The risk of new malignancy (hazard ratio 0.65, p = 0.036) was
significantly lower in the phlebotomy group. Among patients who did
develop cancer, cancer-specific mortality (HR 0.39, p = 0.003) and
all-
cause mortality (HR 0.49, p = 0.009) were lower in the phlebotomy
group.
Overall, 75% of new cancers occurred in patients with mean ferritin
levels > 57 ng/mL.
These findings do not pertain to younger patients without vascular
disease, women, or African Americans, whose ferritin levels are
higher
than those of Caucasians, the investigators say. Instead, "these
observations provide incentive for future studies and insight into
optimal clinical trial design."
Dr. Zacharski's team suggests "there may be a need to redefine the
normal range for the serum ferritin level based on associated disease
risk." They also call for re-evaluation of the policy of routinely
administering iron to anemic cancer patients.
In a related editorial, Dr. Mads Melbye, at Statens Serum Institut in
Copenhagen and colleagues suggest that "these results almost seem to
be too good to be true."
While recommending that "all possibilities for bias must be carefully
examined" and that "the results have to be interpreted with caution,"
the editorialists also support more research on this topic.
Furthermore, they write, "a cautious standpoint toward iron
supplementation where no proper indication exists is perhaps
advisable."
J Natl Cancer Inst 2008;100.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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| ironjustice... |
| Posted: Wed Jul 23, 2008 4:00 pm |
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Guest
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On Jul 23, 3:50 pm, "Cheeky Bastard" <InvalidEm... at (no spam) aol.com> wrote:
testosterone depleted retarded fatboy <<
"THESE RESULTS ALMOST SEEM TOO GOOD TO BE .. TRUE."
Reducing Iron Stores by Phlebotomy Lowers Cancer Risk in Older Men
NEW YORK (Reuters Health) Jul 08 - Cancer incidence and mortality in
older men may be reduced by repeated phlebotomy to lower serum
ferritin levels, according to findings published online on July 8 in
the Journal of the National Cancer Institute.
Observational studies suggest that lower body iron stores may protect
against malignancy by reducing iron-induced oxidative stress, Dr. Leo
R. Zacharski and his associates note.
To test this possibility, Dr. Zacharski, at the White River Junction
Veterans Affairs Medical Center, Vermont, and his group conducted an
ad hoc analysis of data from a VA study in which patients with
peripheral arterial disease were assigned to repeated blood
collections (n = 636) or to a control group (n = 641), originally for
prevention of atherosclerotic complications .
The population was 99% male, mean age 67 years, with mean ferritin
levels at baseline of 122 ng/mL. Phlebotomy was scheduled every 6
months to maintain ferritin levels between 25 and 60 ng/mL. During a
mean follow-up of 4.5 years, there were 60 new visceral malignancies
in the control patients and 38 in the iron-reduction patients (p 0.023).
The risk of new malignancy (hazard ratio 0.65, p = 0.036) was
significantly lower in the phlebotomy group. Among patients who did
develop cancer, cancer-specific mortality (HR 0.39, p = 0.003) and
all-
cause mortality (HR 0.49, p = 0.009) were lower in the phlebotomy
group.
Overall, 75% of new cancers occurred in patients with mean ferritin
levels > 57 ng/mL.
These findings do not pertain to younger patients without vascular
disease, women, or African Americans, whose ferritin levels are
higher
than those of Caucasians, the investigators say. Instead, "these
observations provide incentive for future studies and insight into
optimal clinical trial design."
Dr. Zacharski's team suggests "there may be a need to redefine the
normal range for the serum ferritin level based on associated disease
risk." They also call for re-evaluation of the policy of routinely
administering iron to anemic cancer patients.
In a related editorial, Dr. Mads Melbye, at Statens Serum Institut in
Copenhagen and colleagues suggest that "these results almost seem to
be too good to be true."
While recommending that "all possibilities for bias must be carefully
examined" and that "the results have to be interpreted with caution,"
the editorialists also support more research on this topic.
Furthermore, they write, "a cautious standpoint toward iron
supplementation where no proper indication exists is perhaps
advisable."
J Natl Cancer Inst 2008;100.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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| ironjustice... |
| Posted: Wed Jul 23, 2008 4:01 pm |
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Guest
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On Jul 23, 11:42 am, ironjustice <teamtan... at (no spam) hotmail.com> wrote:
Reducing Iron Stores <<
"THESE RESULTS ALMOST SEEM TOO GOOD TO BE .. TRUE."
Reducing Iron Stores by Phlebotomy Lowers Cancer Risk in Older Men
NEW YORK (Reuters Health) Jul 08 - Cancer incidence and mortality in
older men may be reduced by repeated phlebotomy to lower serum
ferritin levels, according to findings published online on July 8 in
the Journal of the National Cancer Institute.
Observational studies suggest that lower body iron stores may protect
against malignancy by reducing iron-induced oxidative stress, Dr. Leo
R. Zacharski and his associates note.
To test this possibility, Dr. Zacharski, at the White River Junction
Veterans Affairs Medical Center, Vermont, and his group conducted an
ad hoc analysis of data from a VA study in which patients with
peripheral arterial disease were assigned to repeated blood
collections (n = 636) or to a control group (n = 641), originally for
prevention of atherosclerotic complications .
The population was 99% male, mean age 67 years, with mean ferritin
levels at baseline of 122 ng/mL. Phlebotomy was scheduled every 6
months to maintain ferritin levels between 25 and 60 ng/mL. During a
mean follow-up of 4.5 years, there were 60 new visceral malignancies
in the control patients and 38 in the iron-reduction patients (p 0.023).
The risk of new malignancy (hazard ratio 0.65, p = 0.036) was
significantly lower in the phlebotomy group. Among patients who did
develop cancer, cancer-specific mortality (HR 0.39, p = 0.003) and
all-
cause mortality (HR 0.49, p = 0.009) were lower in the phlebotomy
group.
Overall, 75% of new cancers occurred in patients with mean ferritin
levels > 57 ng/mL.
These findings do not pertain to younger patients without vascular
disease, women, or African Americans, whose ferritin levels are
higher
than those of Caucasians, the investigators say. Instead, "these
observations provide incentive for future studies and insight into
optimal clinical trial design."
Dr. Zacharski's team suggests "there may be a need to redefine the
normal range for the serum ferritin level based on associated disease
risk." They also call for re-evaluation of the policy of routinely
administering iron to anemic cancer patients.
In a related editorial, Dr. Mads Melbye, at Statens Serum Institut in
Copenhagen and colleagues suggest that "these results almost seem to
be too good to be true."
While recommending that "all possibilities for bias must be carefully
examined" and that "the results have to be interpreted with caution,"
the editorialists also support more research on this topic.
Furthermore, they write, "a cautious standpoint toward iron
supplementation where no proper indication exists is perhaps
advisable."
J Natl Cancer Inst 2008;100.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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| Cheeky Bastard... |
| Posted: Wed Jul 23, 2008 5:47 pm |
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Guest
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LOL True
"Michael B" <baughfam at (no spam) bellsouth.net> wrote in message
news:2280f537-41bb-473a-8f79-a0218dc1f5bd at (no spam) f63g2000hsf.googlegroups.com...
Don't discourage him from making an actual observation.
He could possibly show us that he can actually review the
available information and make a valid assessment. He would
still have issues with causality, but one thing at a time.
On Jul 23, 12:18 am, "Cheeky Bastard" <InvalidEm... at (no spam) aol.com> wrote:
Quote: Your right! YOU DON'T THINK!
CB"ironjustice" <teamtan... at (no spam) hotmail.com> wrote in message
news:ce38a0ff-54a6-4e95-b885-6cf3cc587138 at (no spam) y21g2000hsf.googlegroups.com...
On Jul 22, 12:51 pm, California Poppy <GoldenStatePo... at (no spam) aol.com
wrote:I wonder how blood thinners such as aspirin affect the results?
So blood thinners reflect iron levels in the body .. ?
Do blood thinners have .. anything .. to DO with .. the .. ferritin ..
that marker they use to assess the amount of iron the human body has
in it .. ?
I don't think blood thinners would affect the results at all.
The iron / ferritin levels would theoretically remain the same {actual
iron chelation and removal with aspirin hasn't been tested] and
therefore the finding of "low iron allows you to remain alive and high
iron levels tend to kill you".
Who loves ya.
Tom |
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| Cheeky Bastard... |
| Posted: Wed Jul 23, 2008 5:50 pm |
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Guest
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Sorry Charlie, it's not "yours"
"ironjustice" <teamtanner at (no spam) hotmail.com> wrote in message
news:6f8f088a-6961-4e38-b85f-28b04fe94deb at (no spam) 56g2000hsm.googlegroups.com...
On Jul 22, 9:18 pm, "Cheeky Bastard" <InvalidEm... at (no spam) aol.com>
wrote:testosterone depleted retarded fatboy <<
You were told to stay off my threads ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
Quote: Your right! YOU DON'T THINK!
CB"ironjustice" <teamtan... at (no spam) hotmail.com> wrote in message
news:ce38a0ff-54a6-4e95-b885-6cf3cc587138 at (no spam) y21g2000hsf.googlegroups.com...
On Jul 22, 12:51 pm, California Poppy <GoldenStatePo... at (no spam) aol.com
wrote:I wonder how blood thinners such as aspirin affect the results?
So blood thinners reflect iron levels in the body .. ?
Do blood thinners have .. anything .. to DO with .. the .. ferritin ..
that marker they use to assess the amount of iron the human body has
in it .. ?
I don't think blood thinners would affect the results at all.
The iron / ferritin levels would theoretically remain the same {actual
iron chelation and removal with aspirin hasn't been tested] and
therefore the finding of "low iron allows you to remain alive and high
iron levels tend to kill you".
Who loves ya.
Tom
Jesus Was A Vegetarian!http://tinyurl.com/2r2nkh
Man Is A Herbivore!http://tinyurl.com/4rq595
DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
On Jul 21, 5:06�pm, ironjustice <teamtan... at (no spam) hotmail.com> wrote:> "These
results almost seem to be too good to be true."
I wonder how blood thinners such as aspirin affect the results?- Hide
quoted text -
- Show quoted text - |
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| ... |
| Posted: Thu Jul 24, 2008 6:15 am |
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Guest
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On Wed, 23 Jul 2008 19:00:37 -0700 (PDT), ironjustice
<teamtanner at (no spam) hotmail.com> wrote:
Quote: On Jul 23, 3:50 pm, "Cheeky Bastard" <InvalidEm... at (no spam) aol.com> wrote:
testosterone depleted retarded fatboy
"THESE RESULTS ALMOST SEEM TOO GOOD TO BE .. TRUE."
Reducing Iron Stores by Phlebotomy Lowers Cancer Risk in Older Men
.......(.shoveled out low-iron horsemanure.)
Justice, whey don't you just buy and take those iron supplements like
the doctor told you to? They're cheap, and the only side effect is
blackened dooky. Your hemoglobin will come up to normal, and you won't
have to search all over the world for some dumb concocted crap about
the beneifts of low iron.
That remark by the nurse about your iron level being ok for a female
was in no way meant to demean you: she was just making a standard
observation. |
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| ironjustice... |
| Posted: Tue Jul 29, 2008 4:38 pm |
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Guest
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"THESE RESULTS ALMOST SEEM TOO GOOD TO BE .. TRUE."
Reducing Iron Stores by Phlebotomy Lowers Cancer Risk in Older Men
NEW YORK (Reuters Health) Jul 08 - Cancer incidence and mortality in
older men may be reduced by repeated phlebotomy to lower serum
ferritin levels, according to findings published online on July 8 in
the Journal of the National Cancer Institute.
Observational studies suggest that lower body iron stores may protect
against malignancy by reducing iron-induced oxidative stress, Dr. Leo
R. Zacharski and his associates note.
To test this possibility, Dr. Zacharski, at the White River Junction
Veterans Affairs Medical Center, Vermont, and his group conducted an
ad hoc analysis of data from a VA study in which patients with
peripheral arterial disease were assigned to repeated blood
collections (n = 636) or to a control group (n = 641), originally for
prevention of atherosclerotic complications .
The population was 99% male, mean age 67 years, with mean ferritin
levels at baseline of 122 ng/mL. Phlebotomy was scheduled every 6
months to maintain ferritin levels between 25 and 60 ng/mL. During a
mean follow-up of 4.5 years, there were 60 new visceral malignancies
in the control patients and 38 in the iron-reduction patients (p =
0.023).
The risk of new malignancy (hazard ratio 0.65, p = 0.036) was
significantly lower in the phlebotomy group. Among patients who did
develop cancer, cancer-specific mortality (HR 0.39, p = 0.003) and
all-
cause mortality (HR 0.49, p = 0.009) were lower in the phlebotomy
group.
Overall, 75% of new cancers occurred in patients with mean ferritin
levels > 57 ng/mL.
These findings do not pertain to younger patients without vascular
disease, women, or African Americans, whose ferritin levels are
higher
than those of Caucasians, the investigators say. Instead, "these
observations provide incentive for future studies and insight into
optimal clinical trial design."
Dr. Zacharski's team suggests "there may be a need to redefine the
normal range for the serum ferritin level based on associated disease
risk." They also call for re-evaluation of the policy of routinely
administering iron to anemic cancer patients.
In a related editorial, Dr. Mads Melbye, at Statens Serum Institut in
Copenhagen and colleagues suggest that "these results almost seem to
be too good to be true."
While recommending that "all possibilities for bias must be carefully
examined" and that "the results have to be interpreted with caution,"
the editorialists also support more research on this topic.
Furthermore, they write, "a cautious standpoint toward iron
supplementation where no proper indication exists is perhaps
advisable."
J Natl Cancer Inst 2008;100.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk |
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