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Science Forum Index » Medicine Forum » Choline and Cognition...
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| ironjustice... |
 Posted: Thu Jul 03, 2008 3:48 am |
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Public release date: 2-Jul-2008
Contact: Cody Mooneyhan
cmooneyhan at (no spam) faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Get smart about what you eat and you might actually improve your
intelligence
MIT researchers offer tantalizing evidence on how to make people
smarter, naturally
New research findings published online in The FASEB Journal provide
more evidence that if we get smart about what we eat, our intelligence
can improve. According to MIT scientists, dietary nutrients found in a
wide range of foods from infant formula to eggs increase brain
synapses and improve cognitive abilities.
"I hope human brains will, like those of experimental animals, respond
to this kind of treatment by making more brain synapses and thus
restoring cognitive abilities," said Richard Wurtman, MD, senior
researcher on the project.
In the study, gerbils were given various combinations of three
compounds needed for healthy brain membranes: choline, found in eggs;
uridine monophosphate (UMP) found in beets; and docosahexaenoic acid
(DHA), found in fish oils. Other gerbils were given none of these to
serve as a baseline. Then they were checked for cognitive changes four
weeks later. The scientists found that the gerbils given choline with
UMP and/or DHA showed cognitive improvements in tasks thought to be
relevant to gerbils, such as navigating mazes. After these tests were
concluded, the researchers dissected the mouse brains for a biological
cause for the improvement. They found biochemical evidence that there
was more than the usual amount of brain synapse activity, which was
consistent with behaviors indicating higher intelligence.
"Now that we know how to make gerbils smarter," said Gerald Weissmann,
MD, Editor-in-Chief of The FASEB Journal, "it's not too far a stretch
to hope that people's intelligence can also be improved. Quite
frankly, this can't happen soon enough, as every environmentalist,
advocate of evolution and war opponent will attest."
###
This article is scheduled for final publication in the November 2008
issue of The FASEB Journal (http://www.fasebj.org), which is published
by the Federation of American Societies for Experimental Biology
(FASEB) and is the most cited biology journal worldwide according to
the Institute for Scientific Information. FASEB comprises 21 nonprofit
societies with more than 80,000 members, making it the largest
coalition of biomedical research associations in the United States.
FASEB advances biological science through collaborative advocacy for
research policies that promote scientific progress and education and
lead to improvements in human health.
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<<snip>>
Lecithin may therefore be the method of choice for
accelerating acetylcholine synthesis
<<snip>>
Lancet. 1977 Jul 9;2(8028):68-9. Related Articles, Links
Lecithin consumption raises serum-free-choline levels.
Wurtman RJ, Hirsch MJ, Growdon JH.
Consumption of choline by rats sequentially increases serum-choline,
brain-choline, and brain-acetylcholine concentrations. In man
consumption of choline increases in levels in the serum and
cerebrospinal fluid; its administration is an effective way of
treating
tardive dyskinesia. We found that oral lecithin is considerably more
effective in raising human serum-choline levels than an equivalent
quantity of choline chloride. 30 minutes after ingestion of choline
chloride (2-3 g free base), serum-choline levels rose by 86% and
returned to normal values within 4 hours; 1 hour after lecithin
ingestion, these levels rose by 265% and remained significantly
raised
for 12 hours. Lecithin may therefore be the method of choice for
accelerating acetylcholine synthesis by increasing the availability
of
choline, its precursor in the blood.
PMID: 69151 [PubMed - indexed for MEDLINE]
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Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
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