Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
thanks tom
every time you post it, it proves you wrong...by your own hand
odd as it would appear, that must be what you want
ironjustice wrote:
On Jun 13, 3:06 pm, "Paul T. Holland" <pholl... at (no spam) bellatlantic.net
wrote:long winded whack
Br J Haematol. 2006 Aug;134(4):438-44. Epub 2006 Jul 4.Related
Articles, Links
Comment in:
Br J Haematol. 2006 Oct;135(2):271-2.
Effect of enhanced iron chelation therapy on glucose metabolism in
patients with beta-thalassaemia major.
Farmaki K, Angelopoulos N, Anagnostopoulos G, Gotsis E, Rombopoulos
G,
Tolis G.
Haematological Department, Korinthos General Hospital, Korinthos,
Greece.
Recently introduced chelation regimens that combine deferoxamine
(DFO)
and deferiprone have been shown to have greater efficacy in promoting
iron excretion than either chelator alone and have been associated
with rapid reduction of the iron load in the heart and liver, and
with
reversal of cardiac dysfunction. It is unclear whether this combined
therapy could be associated with a reduction in iron load or decline
in the severity of iron-induced endocrinopathies. Starting in January
2001, 42 patients with beta-thalassaemia major, previously maintained
on subcutaneous DFO only, were switched to combined treatment with
DFO
and deferiprone. The primary endpoint was to investigate the effects
of this therapy on the glucose metabolism characteristics of this
population. Combination therapy markedly decreased ferritin levels
(638 +/- 1345 vs. 2991 +/- 2093 microg/l, P < 0.001). Glucose
responses were improved at all times during an oral glucose tolerance
test, particularly in patients in early stages of glucose
intolerance.
Glucose quantitative secretion also decreased significantly with
combined therapy, while no significant change occurred in insulin
levels in any group. Insulin secretion, according to the homeostasis
assessment model, markedly increased in all groups, while overall
reduction in insulin sensitivity did not reach statistical
significance. This study showed that the combination of DFO and
deferiprone was associated with an improvement in liver iron
deposition and glucose intolerance.
PMID: 16822284 [PubMed - indexed for MEDLINE]
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk- Hide quoted text -
- Show quoted text -
