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Science Forum Index » Medicine - Vision Forum » Xalatin drops dosage...
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| Don W... |
 Posted: Sun May 18, 2008 2:35 pm |
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When using Xalatin, the directions say that one should not "double drop".
That this tends to minimize the effectiveness of the medication. Really
don't understand this. If one puts in too much, the overflow goes down the
nasal duct. And it is the percent solution that stays in the eye along with
the initial tear volume that determines how much medication the eye gets.
Does dropping in the second drop produce a tearing reaction that dilutes
the concentration of the entire 2 drop volume? Seems like that is what is
happening.
Don W. |
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| David Robins, MD... |
| Posted: Sun May 18, 2008 11:59 pm |
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On 5/18/08 12:35 PM, in article 1y%Xj.5760$r82.2313 at (no spam) nlpi069.nbdc.sbc.com,
"Don W" <dwilgus at (no spam) prodigy.net> wrote:
Quote: When using Xalatin, the directions say that one should not "double drop".
That this tends to minimize the effectiveness of the medication. Really
don't understand this. If one puts in too much, the overflow goes down the
nasal duct. And it is the percent solution that stays in the eye along with
the initial tear volume that determines how much medication the eye gets.
Does dropping in the second drop produce a tearing reaction that dilutes
the concentration of the entire 2 drop volume? Seems like that is what is
happening.
Don W.
Xalatan tends to cause darkening of the skin when it gets on the skin
chronically. "Double-dropping" tends to get the excess squeezed out onto the
skin where it causes this (dark rings under the eyes). To help prevent this,
even with one drop, it is a good idea to wash the eyelids skin off after
instilling the drop. (It also sometimes causes darkening and growth of
eyelashes, but rinsing off will not prevent this. Now, if they could just
figure out how to package this for people who want this eyelash effect ...)
Some of the excess does go into the tear ducts as mentioned.
On a different note, it is to be dosed only once a day. More frequent use
may recuce its pressure-lowering effects. Xalatan works by causing a type of
inflammation of the sclera, causing scleral outflow. Too much inflammation
reduces this effect. |
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