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Science Forum Index  »  Immunology Forum  »  Aluminum is a heavy metal AND a neurotoxin
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Jan Drew
Posted: Thu May 25, 2006 11:07 pm
Guest
Therefore should NOT be injected into humans.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9017255&query_hl=2&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2198876&query_hl=2&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1677837&query_hl=2&itool=pubmed_docsum

Neurochemical hypothesis: participation by aluminum in producing critical
mass of colocalized errors in brain leads to neurological disease.

Joshi JG.

Department of Biochemistry, University of Tennessee, Knoxville 37996-0840.

1. Aluminum is an established neurotoxin. Prolonged exposure to even low
levels of aluminum permit its chelation and subsequent transport to brain
where it is non-uniformly distributed. 2. Available evidence suggests that
(i) aluminum interferes with glucose metabolism by inhibiting hexokinase and
glucose-6-phosphate dehydrogenase; (ii) it binds to calmodulin and affects
numerous phosphorylation-dephosphorylation reactions; (iii) it binds to
transferrin and ferritin, affects the function of these proteins which in
turn affect iron metabolism. 3. Thus accumulation of aluminum-induced
metabolic errors colocalized in specific areas of the brain may lead to
neurological disorders.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15202764&query_hl=11&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11746431&query_hl=11&itool=pubmed_DocSum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11470325&query_hl=11&itool=pubmed_DocSum

[for starters]
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