http://www.sciencedaily.com/releases/2007/03/070313150435.htm
As scientists learn more about the key role of inflammation in diabetes, heart
disease and other disorders, new research from Washington University School of
Medicine in St. Louis suggests that fat in the belly may be an important
promoter of that inflammation.
Excess fat is known to be associated with disease, but now the researchers have
confirmed that fat cells inside the abdomen are secreting molecules that increase
inflammation. It's the first evidence of a potential mechanistic link between
abdominal fat and systemic inflammation.
For years, scientists have been aware of a relationship between disease risk and
excess belly fat. "Apple-shaped" people, who carry fat in the abdomen, have a
higher risk of heart disease, diabetes and other problems than "pear-shaped"
people, who tend to store fat in the hips and thighs. Too much abdominal fat is
associated with a defect in the body's response to insulin.
...
In this new study, researchers looked instead at visceral fat -- the fat that
surrounds the organs in the gut.
...
Reporting in the journal Diabetes, the research team says visceral fat likely
contributes to increases in systemic inflammation and insulin resistance.
...
Fat humans are unhealthy humans.