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Guest
Posted: Wed Feb 28, 2007 8:23 am
BP was nicely under control, 130-75, using Adalat nifedipine 90mg.
Switched to generic, Mylan labs 90mg and BP soared to 145-95, tested
for a week. Placed a pill of each in water. After two hours the Adalat
brand had softened and began to breakdown. The Myan pill lost it's
cosmetic coating but was hard and and same size. Is anyone aware of
this problem? Can the generic pill be cut in half safely to speed
absorbtion?

Tom
Jeff
Posted: Wed Feb 28, 2007 10:04 am
Guest
<theodoric3@lycos.com> wrote in message
news:1172665416.595457.186810@m58g2000cwm.googlegroups.com...
Quote:
BP was nicely under control, 130-75, using Adalat nifedipine 90mg.
Switched to generic, Mylan labs 90mg and BP soared to 145-95, tested
for a week. Placed a pill of each in water. After two hours the Adalat
brand had softened and began to breakdown. The Myan pill lost it's
cosmetic coating but was hard and and same size. Is anyone aware of
this problem? Can the generic pill be cut in half safely to speed
absorbtion?

Call your doctor. Your blood pressure could be high for other reasons. In
addition, your doctor may know if this is a common occurance.

Alternatively, you take an Adalat pill, if you have any left and call your
doc if the blood pressure doesn't go down.

If your blood pressure goes back down, I would take all the Mylan pills to
the pharmacist, tell her what happened and ask either they be replaced with
Adalat or you get your money back. And I would go fda.gov, click on Report a
Problem with a product, and file an Adverse Event report. Also, ask you doc
about this at the next visit if your BP stays down.

The stomach pH is low, about 1. This is very acidic. The Mylan labs pills
might dissolve in your stomach faster.

Jeff

Quote:
Tom
William Wagner
Posted: Wed Feb 28, 2007 10:26 am
Guest
In article <8_fFh.11253$tA1.1697@trndny02>,
"Jeff" <news@googlemail.com> wrote:

Quote:
theodoric3@lycos.com> wrote in message
news:1172665416.595457.186810@m58g2000cwm.googlegroups.com...
BP was nicely under control, 130-75, using Adalat nifedipine 90mg.
Switched to generic, Mylan labs 90mg and BP soared to 145-95, tested
for a week. Placed a pill of each in water. After two hours the Adalat
brand had softened and began to breakdown. The Myan pill lost it's
cosmetic coating but was hard and and same size. Is anyone aware of
this problem? Can the generic pill be cut in half safely to speed
absorbtion?

Call your doctor. Your blood pressure could be high for other reasons. In
addition, your doctor may know if this is a common occurance.

Alternatively, you take an Adalat pill, if you have any left and call your
doc if the blood pressure doesn't go down.

If your blood pressure goes back down, I would take all the Mylan pills to
the pharmacist, tell her what happened and ask either they be replaced with
Adalat or you get your money back. And I would go fda.gov, click on Report a
Problem with a product, and file an Adverse Event report. Also, ask you doc
about this at the next visit if your BP stays down.

The stomach pH is low, about 1. This is very acidic. The Mylan labs pills
might dissolve in your stomach faster.

Jeff

Tom


Good advice Jeff ! I was thinking about possible counterfeit drugs.

Bill

--

S Jersey USA Zone 5 Shade
http://www.ocutech.com/ High tech Vison aid
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.
Jeff
Posted: Wed Feb 28, 2007 10:53 am
Guest
"William Wagner" <not-to-here-williamwag@gmail.com> wrote in message
news:not-to-here-williamwag-C77CC5.09264128022007@sn-indi.vsrv-sjc.supernews.net...
Quote:
In article <8_fFh.11253$tA1.1697@trndny02>,
"Jeff" <news@googlemail.com> wrote:

theodoric3@lycos.com> wrote in message
news:1172665416.595457.186810@m58g2000cwm.googlegroups.com...
BP was nicely under control, 130-75, using Adalat nifedipine 90mg.
Switched to generic, Mylan labs 90mg and BP soared to 145-95, tested
for a week. Placed a pill of each in water. After two hours the Adalat
brand had softened and began to breakdown. The Myan pill lost it's
cosmetic coating but was hard and and same size. Is anyone aware of
this problem? Can the generic pill be cut in half safely to speed
absorbtion?

Call your doctor. Your blood pressure could be high for other reasons. In
addition, your doctor may know if this is a common occurance.

Alternatively, you take an Adalat pill, if you have any left and call
your
doc if the blood pressure doesn't go down.

If your blood pressure goes back down, I would take all the Mylan pills
to
the pharmacist, tell her what happened and ask either they be replaced
with
Adalat or you get your money back. And I would go fda.gov, click on
Report a
Problem with a product, and file an Adverse Event report. Also, ask you
doc
about this at the next visit if your BP stays down.

The stomach pH is low, about 1. This is very acidic. The Mylan labs pills
might dissolve in your stomach faster.

Jeff

Tom


Good advice Jeff ! I was thinking about possible counterfeit drugs.

Good thinking.

The OP should look on the web site for mylan and see if the pills have the
right markings:
http://www.mylanpharms.com/product/productDetails.aspx?pid=105&query=1 If
the pills don't have the proper markings, they're the wrong pills. Could be
that the pharmacist pulled the wrong bottle of pills, the pills were packed
wrong at the factory, or the pills are conterfeit.If they have the right
markings, particularly if the markings look a little different, they could
still be counterfeit.

I am not sure why, the Adalat CC has a core or center that is rapid release
and a slow release coating. I would have thought the core would be slow
release, but the coating would be rapid release (so that the blood levels
get to their values fast, and the slow release keeps them there). Anyway, if
this is the case, breaking a pill in half may cause a rapid increase in
blood levels and dangeriously low blood pressure.

Jeff

Jeff

Quote:
Bill

--

S Jersey USA Zone 5 Shade
http://www.ocutech.com/ High tech Vison aid
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.
Guest
Posted: Wed Feb 28, 2007 11:10 am
On Feb 28, 7:53 am, "Jeff" <n...@googlemail.com> wrote:
Quote:
"William Wagner" <not-to-here-william...@gmail.com> wrote in message

news:not-to-here-williamwag-C77CC5.09264128022007@sn-indi.vsrv-sjc.supernews.net...





In article <8_fFh.11253$tA1.1697@trndny02>,
"Jeff" <n...@googlemail.com> wrote:

theodor...@lycos.com> wrote in message
news:1172665416.595457.186810@m58g2000cwm.googlegroups.com...
BP was nicely under control, 130-75, using Adalat nifedipine 90mg.
Switched to generic, Mylan labs 90mg and BP soared to 145-95, tested
for a week. Placed a pill of each in water. After two hours the Adalat
brand had softened and began to breakdown. The Myan pill lost it's
cosmetic coating but was hard and and same size. Is anyone aware of
this problem? Can the generic pill be cut in half safely to speed
absorbtion?

Call your doctor. Your blood pressure could be high for other reasons. In
addition, your doctor may know if this is a common occurance.

Alternatively, you take an Adalat pill, if you have any left and call
your
doc if the blood pressure doesn't go down.

If your blood pressure goes back down, I would take all the Mylan pills
to
the pharmacist, tell her what happened and ask either they be replaced
with
Adalat or you get your money back. And I would go fda.gov, click on
Report a
Problem with a product, and file an Adverse Event report. Also, ask you
doc
about this at the next visit if your BP stays down.

The stomach pH is low, about 1. This is very acidic. The Mylan labs pills
might dissolve in your stomach faster.

Jeff

Tom

Good advice Jeff ! I was thinking about possible counterfeit drugs.

Good thinking.

The OP should look on the web site for mylan and see if the pills have the
right markings:http://www.mylanpharms.com/product/productDetails.aspx?pid=105&query=1If
the pills don't have the proper markings, they're the wrong pills. Could be
that the pharmacist pulled the wrong bottle of pills, the pills were packed
wrong at the factory, or the pills are conterfeit.If they have the right
markings, particularly if the markings look a little different, they could
still be counterfeit.

I am not sure why, the Adalat CC has a core or center that is rapid release
and a slow release coating. I would have thought the core would be slow
release, but the coating would be rapid release (so that the blood levels
get to their values fast, and the slow release keeps them there). Anyway, if
this is the case, breaking a pill in half may cause a rapid increase in
blood levels and dangeriously low blood pressure.

Jeff

Jeff



Bill

--

S Jersey USA Zone 5 Shade
http://www.ocutech.com/ High tech Vison aid
This article is posted under fair use rules in accordance with
Title 17 U.S.C. Section 107, and is strictly for the educational
and informative purposes. This material is distributed without profit.- Hide quoted text -

- Show quoted text -- Hide quoted text -

- Show quoted text -

I checked the pill markings and o.k., the VA was the source, they
switched from Adalat to the generic. Since the VA
no longer uses Adalat I am working with Doc on another approach.
(switched back to Adalat this am, one hour after taking
bp 134-82) Thanks everyone for your suggestions.

Tom
Jeff
Posted: Wed Feb 28, 2007 12:16 pm
Guest
<theodoric3@lycos.com> wrote in message
news:1172675439.294564.272850@8g2000cwh.googlegroups.com...
<...>

Quote:
I checked the pill markings and o.k., the VA was the source, they
switched from Adalat to the generic. Since the VA
no longer uses Adalat I am working with Doc on another approach.
(switched back to Adalat this am, one hour after taking
bp 134-82) Thanks everyone for your suggestions.

I would call your doc and the VA pharmacist and tell them what happened. If
this happened to you, how many vets did this happen to who don't check their
blood pressure regularly?

Also, go to fda.gov and report this.

Also, call your local Walmart and see how much the drug is. It may be cheep
enough (like under $10) that you won't care about the money.

Jeff


Quote:
Tom
Guest
Posted: Wed Feb 28, 2007 3:46 pm
On Feb 28, 9:16 am, "Jeff" <n...@googlemail.com> wrote:
Quote:
theodor...@lycos.com> wrote in message

news:1172675439.294564.272850@8g2000cwh.googlegroups.com...
...

I checked the pill markings and o.k., the VA was the source, they
switched from Adalat to the generic. Since the VA
no longer uses Adalat I am working with Doc on another approach.
(switched back to Adalat this am, one hour after taking
bp 134-82) Thanks everyone for your suggestions.

I would call your doc and the VA pharmacist and tell them what happened. If
this happened to you, how many vets did this happen to who don't check their
blood pressure regularly?

Also, go to fda.gov and report this.

Also, call your local Walmart and see how much the drug is. It may be cheep
enough (like under $10) that you won't care about the money.

Jeff



Tom- Hide quoted text -

- Show quoted text -

I emailed Mylan Labs early this am and a young lady called and I
reviewed the tests. She said the product was made by Pfizer and the
chemical structure was differnat then the Adalat product saying theirs
was same as Procardia. I've alerted the
various veterans sites re: checking and rechecking their BP if they
too had their meds. changed.

Tom
 
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