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| Science Forum Index » Medicine - Cardiology Forum » Artificial sweetener use linked with kidney failure... |
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| Andrew B. Chung, MD/PhD... |
 Posted: Wed Nov 04, 2009 4:16 pm |
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| Steve Hayes... |
| Posted: Wed Nov 04, 2009 10:21 pm |
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On Wed, 04 Nov 2009 16:16:46 -0500, "Andrew B. Chung, MD/PhD"
<achung at (no spam) emory.edu> wrote:
[quote]"Over the 11-year period, 372 women (11.4%) experienced an eGFR
decline of 30% or greater. On multivariate analysis, compared with
consumption of less than 1 artificially sweetened soda per month, 2 or
more per day doubled the risk of a 30% or greater decline in kidney
function (odds ratio 2.02).
The highest consumption category was also associated with increased
risk of an annual decline of at least 3 mL/min/1.73 m2 (odds ratio
2.20). On the other hand, there was no increased risk for eGFR decline
with less than 2 servings per day of artificially sweetened soda.
[/quote]
Did they say which sweeteners were used, and test them separately?
--
Steve Hayes from Tshwane, South Africa
Web: http://hayesfam.bravehost.com/stevesig.htm
Blog: http://methodius.blogspot.com
E-mail - see web page, or parse: shayes at dunelm full stop org full stop uk |
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| trigonometry1972 at (no spam) gmail.com |... |
| Posted: Wed Nov 04, 2009 10:26 pm |
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On Nov 4, 7:21 pm, Steve Hayes <hayesm... at (no spam) hotmail.com> wrote:
[quote]On Wed, 04 Nov 2009 16:16:46 -0500, "Andrew B. Chung, MD/PhD"
ach... at (no spam) emory.edu> wrote:
"Over the 11-year period, 372 women (11.4%) experienced an eGFR
decline of 30% or greater. On multivariate analysis, compared with
consumption of less than 1 artificially sweetened soda per month, 2 or
more per day doubled the risk of a 30% or greater decline in kidney
function (odds ratio 2.02).
The highest consumption category was also associated with increased
risk of an annual decline of at least 3 mL/min/1.73 m2 (odds ratio
2.20). On the other hand, there was no increased risk for eGFR decline
with less than 2 servings per day of artificially sweetened soda.
Did they say which sweeteners were used, and test them separately?
--
Steve Hayes from Tshwane, South Africa
Web: http://hayesfam.bravehost.com/stevesig.htm
Blog:http://methodius.blogspot.com
E-mail - see web page, or parse: shayes at dunelm full stop org full stop uk
[/quote]
It doesn't seem so. What I find worrying and it maybe a function
of the reporting, is that obesity and diabetes should over time
have a direct relationship with kidney function decline. Perhaps
what was meant was that this was allowed for and the decline
in kidney function was greater in those using these sweeteners.
And I agree it would be nice to know which these sweetners
presents the risk. Unless the mechanism of harm is
something in common between artificial sweetners?
Personally I avoid all sweeteners natural, caloric, non-caloric, and
artificial. I will admit to consuming some relatively unprocessed
fruit
in limited portions. |
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| Andrew B. Chung, MD/PhD... |
| Posted: Thu Nov 05, 2009 1:28 am |
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trigonometry1972 at (no spam) gmail.com | wrote:
[quote]Steve Hayes wrote:
Andrew, in the Holy Spirit, boldly wrote:
"Over the 11-year period, 372 women (11.4%) experienced an eGFR
decline of 30% or greater. On multivariate analysis, compared with
consumption of less than 1 artificially sweetened soda per month, 2 or
more per day doubled the risk of a 30% or greater decline in kidney
function (odds ratio 2.02).
The highest consumption category was also associated with increased
risk of an annual decline of at least 3 mL/min/1.73 m2 (odds ratio
2.20). On the other hand, there was no increased risk for eGFR decline
with less than 2 servings per day of artificially sweetened soda.
Did they say which sweeteners were used, and test them separately?
[/quote]
No.
[quote]It doesn't seem so. What I find worrying and it maybe a function
of the reporting, is that obesity and diabetes should over time
have a direct relationship with kidney function decline. Perhaps
what was meant was that this was allowed for and the decline
in kidney function was greater in those using these sweeteners.
[/quote]
That would be the inferred meaning.
Be hungrier, which truly is healthier especially for the heart and
kidneys:
http://WDJW.net/BeSmart
Love in the truth,
Andrew <><
--
Andrew B. Chung, MD/PhD
Board-certified Heart Doctor
and Author of "Trust the Truth:"
http://www.amazon.com/-/e/B002G22ZWG
http://groups.google.com/group/sci.med.cardiology/msg/9642aafa0aad16eb?
Only the truth can cure the "hunger is starvation" delusion:
http://groups.google.com/group/sci.med.cardiology/msg/74281ab7d7ce78de? |
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| trigonometry1972 at (no spam) gmail.com |... |
| Posted: Thu Nov 05, 2009 3:20 am |
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On Nov 5, 3:28 am, "Andrew B. Chung, MD/PhD" <lo... at (no spam) thetruth.com>
wrote:
[quote]trigonometry1... at (no spam) gmail.com | wrote:
Steve Hayes wrote:
Andrew, in the Holy Spirit, boldly wrote:
"Over the 11-year period, 372 women (11.4%) experienced an eGFR
decline of 30% or greater. On multivariate analysis, compared with
consumption of less than 1 artificially sweetened soda per month, 2 or
more per day doubled the risk of a 30% or greater decline in kidney
function (odds ratio 2.02).
The highest consumption category was also associated with increased
risk of an annual decline of at least 3 mL/min/1.73 m2 (odds ratio
2.20). On the other hand, there was no increased risk for eGFR decline
with less than 2 servings per day of artificially sweetened soda.
Did they say which sweeteners were used, and test them separately?
No.
It doesn't seem so. What I find worrying and it maybe a function
of the reporting, is that obesity and diabetes should over time
have a direct relationship with kidney function decline. Perhaps
what was meant was that this was allowed for and the decline
in kidney function was greater in those using these sweeteners.
That would be the inferred meaning.
[/quote]
I'd like to infer that meaning but that isn't what is said.
Or are you a fan of synthetic sweeteners? I can see it
now Andy with a can of carbonated orange flavor drink
sweetened with aspartame. If there is such a product?
What is your economic plan Andy? Should we all
get bicycles and got to Walmart only every other
month?
A hungrier population is soon to come...............Trig |
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| ... |
| Posted: Thu Nov 05, 2009 9:54 am |
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Guest
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[quote]Did they say which sweeteners were used, and test them separately?
[/quote]
No.
[quote]It doesn't seem so. What I find worrying and it maybe a function
of the reporting, is that obesity and diabetes should over time
have a direct relationship with kidney function decline. Perhaps
what was meant was that this was allowed for and the decline
in kidney function was greater in those using these sweeteners.
[/quote]
"That would be the inferred meaning."
And perhaps the wrong inference.
In such studies one must tease out other factors. One common one is
that people who make one choice, such as diet sodas, are also making
more often other choices which are the valid source of the outcome.
How often do we joke that people load up on fast food and choose the
diet soda to avoid extra calories? |
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| Andrew B. Chung, MD/PhD... |
| Posted: Fri Nov 06, 2009 1:51 am |
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trigonometry1972 at (no spam) gmail.com | wrote:
[quote]Andrew, in the Holy Spirit, boldly wrote:
trigonometry1... at (no spam) gmail.com | wrote:
Steve Hayes wrote:
Andrew, in the Holy Spirit, boldly wrote:
"Over the 11-year period, 372 women (11.4%) experienced an eGFR
decline of 30% or greater. On multivariate analysis, compared with
consumption of less than 1 artificially sweetened soda per month, 2 or
more per day doubled the risk of a 30% or greater decline in kidney
function (odds ratio 2.02).
The highest consumption category was also associated with increased
risk of an annual decline of at least 3 mL/min/1.73 m2 (odds ratio
2.20). On the other hand, there was no increased risk for eGFR decline
with less than 2 servings per day of artificially sweetened soda.
Did they say which sweeteners were used, and test them separately?
No.
It doesn't seem so. What I find worrying and it maybe a function
of the reporting, is that obesity and diabetes should over time
have a direct relationship with kidney function decline. Perhaps
what was meant was that this was allowed for and the decline
in kidney function was greater in those using these sweeteners.
That would be the inferred meaning.
I'd like to infer that meaning but that isn't what is said.
[/quote]
From what is written, the study is too under-powered (N is too small)
to detect small effects such as 11yr renal function decline secondary
to either obesity or diabetes.
Be hungrier, which truly is healthier especially for diabetics:
http://WDJW.net/BeSmart
Love in the truth,
Andrew <><
--
Andrew B. Chung, MD/PhD
Board-certified Heart Doctor
and Author of "Trust the Truth:"
http://www.amazon.com/-/e/B002G22ZWG
http://groups.google.com/group/sci.med.cardiology/msg/9642aafa0aad16eb?
Only the truth can cure the "hunger is starvation" delusion:
http://groups.google.com/group/sci.med.cardiology/msg/74281ab7d7ce78de? |
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