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| Science Forum Index » Medicine - Nutrition Forum » B vitamins increase PUFA content and testis weight... |
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| Taka... |
 Posted: Wed Oct 21, 2009 3:14 pm |
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The Influence of Folic Acid, Vitamins B2 and B6 Supplementation on
Feed Intake, Body and Organs Weight, and Liver Fatty Acids Composition
of Rats Subjected to 3 months Moderate Protein Deprivation
This study was conducted to determine the effect of a 3-month dietary
protein restriction – protein provided 9% of energy (20% in control
group). In this dietary restriction folic acid, vitamins B2 and B6
were delivered in amount three times above the standard level. It was
observed that animals fed a protein restricted (PR) diet weighed about
5% less than animals consuming adequate diet, but the difference was
not statistically significant. Enrichment of PR diet with vitamin B or
folic acid caused tendency to further suppression of weight gain, and
in case of vitamin B6 these differences were statistically
significant. However, such body weight (BW) suppression was not
observed when all studied vitamins were used together. Significant
reductions in relative liver weight (vitamin B2 addition), the heart
(folic acid) and the lungs (vitamin B6) were observed. The PR diet,
when all vitamins were added together, caused a decrease in weights of
the lungs, heart and liver scaled to BW of rats, simultaneously with a
significant increase in testis weight. Feed intake and feed conversion
ratio were higher in animals given PR diet without a significant
influence of vitamin supplementation (except vitamin B6 causing
further increase in feed conversion ratio). Hepatic fatty acids
composition of rats was not affected by protein restriction, as well
as by single vitamin supplementation. However, dietary supplementation
of all examined vitamins together caused a decrease in monounsaturated
fatty acids followed by an increase in polyunsaturated fatty acids
participation in total fatty acids pool. It seems that enrichment of
PR diet with a mixture of folic acid, vitamins B2 and B6 resulted in a
partial reverse of growth suppression and reduction in testis size in
rats.
SOURCE: http://www3.interscience.wiley.com/journal/118541618/abstract?CRETRY=1&SRETRY=0
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I guess B vitamins stimulate Mead acid synthesis during the CR/PR.
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