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Science Forum Index » Life Extension Forum » (Young) Men and women may metabolize fructose...
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 Posted: Fri Jun 06, 2008 9:51 pm |
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Guest
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Probably due to difference in energy-consuming activities between men
and women and/or to ensure reserves for pregnancies, women evolved to
store excess calories in adipose tissue more efficiently while men
spent it all through their daily activities..
Arbor
http://health.yahoo.com/news/reuters/correction_men_women_metabolize_fructose_dc.html
NEW YORK (Reuters Health) - Men and women appear to differ in how they
metabolize high levels of fructose, a simple sugar commonly used to
sweeten drinks and foods.
Short-term high fructose intake among young men resulted in increased
blood triglycerides (fats) and increased insulin resistance, factors
associated with an elevated risk for cardiovascular disease and type 2
diabetes, report Dr. Luc Tappy and colleagues.
Whereas, "women get rid of the excess sugar load in a (likely) less
deleterious way," said Tappy, of Lausanne University School of Biology
and Medicine in Switzerland.
"Hence, gender has to be taken into consideration in studies
evaluating the relationship between nutrition and metabolic
disorders," Tappy told Reuters Health.
Tappy and colleagues enlisted 16 healthy, nonsmoking men and women of
normal weight and about 23 years of age, to follow two different 6-day
diets separated by a 4-week wash-out period.
The 8 men and 8 women did not participate in sports or exercise while
following either the "control" diet or the diet that included a lemon-
flavored drink containing 3.5 grams of fructose.
"The fructose load used in this study was quite large (corresponding
to several liters of sodas per day)," noted Tappy. He and colleagues
tested 12 fasting metabolic parameters the day after participants
completed each diet, they report in Diabetes Care.
In the men, fructose supplementation caused significant increases in
11 of the 12 factors, including a 5 percent increase in fasting
glucose and 71 percent increase in triglyceride levels.
By contrast, women showed a 4 percent increase in glucose and a
"markedly blunted," 16 percent increase in triglycerides after the
high fructose diet, the investigators said. Overall, the women showed
significant increases in only 4 of the 12 factors tested.
Further studies should more accurately identify gender differences in
metabolic pathways and confirm these observations in a larger
population, the investigators note.
"One burning question is whether fructose may have more deleterious
effects in individuals at high risk for metabolic disorders," Tappy
surmises.
SOURCE: Diabetes Care, June 2008. |
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