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Posted: Fri Jun 06, 2008 7:09 am
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Eur J Cardiovasc Prev Rehabil. 2008 Jun;15(3):300-5.

The acute effect of green tea consumption on endothelial function in
healthy individuals.

Alexopoulos N, Vlachopoulos C, Aznaouridis K, Baou K, Vasiliadou C,
Pietri P, Xaplanteris P, Stefanadi E, Stefanadis C.

Peripheral Vessels Unit, First Cardiology Department, Athens Medical
School, Hippokration Hospital, Athens, Greece.

BACKGROUND: Tea consumption is associated with decreased
cardiovascular risk. Flow-mediated dilatation (FMD) of the brachial
artery is related to coronary endothelial function and it is an
independent predictor of cardiovascular risk. Black tea has a
beneficial effect on endothelial function; the effect, however, of
green tea on brachial artery reactivity has not been defined yet.
DESIGN AND METHODS: We studied 14 healthy individuals (age 30+/-3
years) with no cardiovascular risk factors except from smoking (50%)
on three separate occasions on which they took: (a) 6 g of green tea,
(b) 125 mg of caffeine (the amount contained in 6 g of tea), or (c)
hot water. FMD of the brachial artery was measured before each
intervention and 30, 90, and 120 min afterward. High-sensitivity C-
reactive protein, interleukins 6 (Il-6) and 1b (Il-1b), total plasma
antioxidative capacity, and total plasma oxidative status/stress were
measured at baseline and at 120 min after each intervention. RESULTS:
Resting and hyperemic brachial artery diameter did not change either
with tea or with caffeine. FMD increased significantly with tea (by
3.69%, peak at 30 min, P<0.02), whereas it did not change
significantly with caffeine (increase by 1.72%, peak at 30 min, P=NS).
Neither tea nor caffeine had any effect on high-sensitivity C-reactive
protein, Il-6, Il-1b, total plasma antioxidative capacity, or total
plasma oxidative status/stress. CONCLUSION: Green tea consumption has
an acute beneficial effect on endothelial function, assessed with FMD
of the brachial artery, in healthy individuals. This may be involved
in the beneficial effect of tea on cardiovascular risk.

PMID: 18525384 [PubMed - in process]
 
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