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ray...
Posted: Sun May 11, 2008 4:21 pm
Guest
About 2 months ago overnight I developed intermittent double vision
in both eyes. I went to 3 different eye doctors. The first said
cataracts and referred me to a cataract surgeon. The second said I
need new glasses which didn't help.

The cataract surgeon said Fuchs's Cornea Dystrophy.
The cataract surgeon measured cornea thickness 630 right, 645 left,
cornea pressure 17 R 15 L, Guttata grade 3 plus, cell count not
measured. I am getting the morning fuzzy vision. On a home eye
chart morning vision is 20/40 R 20/50 L. In the afternoon it is
20/20 L 20/25 R. I am using Muro eye drops and ointment at night.
It seems to clear the vision somewhat.

I am a 68 year old male. The cataract surgeon said I have some
cataracts, but with the Fuchs's he would not operate.


Questions:
Is Fuchs's that difficult to diagnose?
How common of a condition is it?
How likely is the cataract surgeon to have the right diagnosis?
Do I need a fourth opinion?
Is the onset usually so sudden (overnight)?
Given my history and current state what is the likely progression of
the disease?

Thanks

Ray
Dr Judy...
Posted: Sun May 11, 2008 4:21 pm
Guest
On May 11, 5:21 pm, ray <spamm... at (no spam) do.not.reply.com> wrote:
Quote:
About 2 months ago overnight I developed intermittent double vision
in both eyes. I went to 3 different eye doctors. The first said
cataracts and referred me to a cataract surgeon. The second said I
need new glasses which didn't help.

The cataract surgeon said Fuchs's Cornea Dystrophy.  
The cataract surgeon measured cornea thickness 630 right, 645 left,
cornea pressure 17 R 15 L, Guttata grade 3 plus, cell count not
measured. I am getting the morning fuzzy vision. On a home eye
chart morning vision is 20/40 R 20/50 L. In the afternoon it is
20/20 L 20/25 R. I am using Muro eye drops and ointment at night.
It seems to clear the vision somewhat.

I am a 68 year old male. The cataract surgeon said I have some
cataracts, but with the Fuchs's he would not operate.

Questions:
Is Fuchs's that difficult to diagnose?

Well, the doctor has to look. It also tends to be worse in am and
better later in the day, so might have been missed if you had late day
appointments.

Quote:
How common of a condition is it?
How likely is the cataract surgeon to have the right diagnosis?
Very likely, esp if he is seeing corneal guttata. Muro is the

treatment and since Muro is working, that also confirms the diagnosis.

Quote:
Do I need a fourth opinion?
No


Quote:
Is the onset usually so sudden (overnight)?
Symptoms can onset quickly


Quote:
Given my history and current state what is the likely progression of
the disease?

Hard to predict. Most people do not progress very quickly. Some go on
to need a corneal transplant, most don't

Judy
Don W...
Posted: Sun May 11, 2008 8:46 pm
Guest
Just exactly what causes the "morning fuzziness"?

Don W.
Mike Tyner...
Posted: Sun May 11, 2008 9:07 pm
Guest
The corneal stroma swells and loses transparency if water isn't actively
pumped out.

The endothelium contains the pump.

When the lids are closed overnight, oxygenation drops.

Healthy endothelium has enough reserve to keep the cornea clear overnight.

-MT


"Don W" <dwilgus at (no spam) prodigy.net> wrote in message
news:AkNVj.3320$nW2.1546 at (no spam) nlpi064.nbdc.sbc.com...
Quote:
Just exactly what causes the "morning fuzziness"?

Don W.
Zetsu...
Posted: Wed May 14, 2008 12:05 pm
Guest
On 14 May, 22:17, ray <spamm... at (no spam) do.not.reply.com> wrote:
Quote:
On Wed, 14 May 2008 12:56:02 -0700, "Don W" <dwil... at (no spam) prodigy.net
wrote:

Thanks.

How might the cornea react to Xalantan with this kind of condition?

Also, is the morning "fuzziness" granular or just overall "fuzzy"? (If that
is clear?).

For high contrast items such as point source of light or black print
on white background it is multiple images. In my case sometimes it is
as many as 6 images smeared vertically. For lower contrast it just
looks fuzzy. Removing excess water from the cornea with salt water or
a hair dryer improves vision. What is Xalantan?



Don W.

"Mike Tyner" <mty... at (no spam) mindspring.com> wrote in message
news:BN6dnQqrkNPHO7rVnZ2dnUVZ_r6rnZ2d at (no spam) giganews.com...
The corneal stroma swells and loses transparency if water isn't actively
pumped out.

The endothelium contains the pump.

When the lids are closed overnight, oxygenation drops.

Healthy endothelium has enough reserve to keep the cornea clear overnight.

-MT

"Don W" <dwil... at (no spam) prodigy.net> wrote in message
news:AkNVj.3320$nW2.1546 at (no spam) nlpi064.nbdc.sbc.com...
Just exactly what causes the "morning fuzziness"?

Don W.

Wikipedia says:

Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a
topical medication used for controlling the progression of glaucoma or
ocular hypertension, by reducing intraocular pressure. It is a
prostaglandin analogue that works by increasing the outflow of aqueous
fluid from the eyes.

It is also known by the brand name of Xalatan manufactured by Pfizer.

Possible side effects:

-May cause reddening of the eyes (hyperemia)
-May cause blurred vision;
-May cause eyelid redness;
-May permanently darken eyelashes;
-May cause eye discomfort;
-May eventually cause permanent darkening of the iris to brown
(heterochromia);
-May cause a temporary burning sensation during use.
-May cause thickening of the eyelashes.
-Rarely, herpes simplex keratitis.

[http://en.wikipedia.org/wiki/Xalatan]
Zetsu...
Posted: Wed May 14, 2008 12:17 pm
Guest
Sorry for going off topic for a second, but why do some people spell
the word 'through' as 'thru'? I mean, if you're going to truncate one
word why not just go all out instead of using a half measure. Why not
replace the whole post with words like 4 instead of 'for' or 'u'
instead of 'you'. Or is this how Americans normally spell the word? I
must say, it's much more convenient to say 'thru' instead of 'through'
but being a semantic kind of person I can't help but notice these
small things where people neglect the rules of standard English.
Consistency in speech is always helpful to foreign speakers, too.
Don W...
Posted: Wed May 14, 2008 2:56 pm
Guest
Thanks.

How might the cornea react to Xalantan with this kind of condition?


Also, is the morning "fuzziness" granular or just overall "fuzzy"? (If that
is clear?).


Don W.




"Mike Tyner" <mtyner at (no spam) mindspring.com> wrote in message
news:BN6dnQqrkNPHO7rVnZ2dnUVZ_r6rnZ2d at (no spam) giganews.com...
Quote:
The corneal stroma swells and loses transparency if water isn't actively
pumped out.

The endothelium contains the pump.

When the lids are closed overnight, oxygenation drops.

Healthy endothelium has enough reserve to keep the cornea clear overnight.

-MT


"Don W" <dwilgus at (no spam) prodigy.net> wrote in message
news:AkNVj.3320$nW2.1546 at (no spam) nlpi064.nbdc.sbc.com...
Just exactly what causes the "morning fuzziness"?

Don W.

ray...
Posted: Wed May 14, 2008 4:17 pm
Guest
On Wed, 14 May 2008 12:56:02 -0700, "Don W" <dwilgus at (no spam) prodigy.net>
wrote:

Quote:
Thanks.

How might the cornea react to Xalantan with this kind of condition?


Also, is the morning "fuzziness" granular or just overall "fuzzy"? (If that
is clear?).

For high contrast items such as point source of light or black print

on white background it is multiple images. In my case sometimes it is
as many as 6 images smeared vertically. For lower contrast it just
looks fuzzy. Removing excess water from the cornea with salt water or
a hair dryer improves vision. What is Xalantan?

Quote:


Don W.




"Mike Tyner" <mtyner at (no spam) mindspring.com> wrote in message
news:BN6dnQqrkNPHO7rVnZ2dnUVZ_r6rnZ2d at (no spam) giganews.com...
The corneal stroma swells and loses transparency if water isn't actively
pumped out.

The endothelium contains the pump.

When the lids are closed overnight, oxygenation drops.

Healthy endothelium has enough reserve to keep the cornea clear overnight.

-MT


"Don W" <dwilgus at (no spam) prodigy.net> wrote in message
news:AkNVj.3320$nW2.1546 at (no spam) nlpi064.nbdc.sbc.com...
Just exactly what causes the "morning fuzziness"?

Don W.


Don W...
Posted: Wed May 14, 2008 5:06 pm
Guest
Interesting about too much fluid in the cornea. I always got the impression
the it was my cornea (outside) surface that needed a few blinks to become
more "optically smooth".

How far apart are your multiple images? Degrees, minutes? Those types of
multiple images I do not have.

Xalatan is a glaucoma drug that reduces eye pressure, namely the anterior
chamber (hopefully the posterior tracks), before higher pressure affects the
optic nerve, which affects blood flow to the eye. The drug, goes thru the
entire cornea (and that would include the endothelium). (As far as I
understand it -- no medical type).

Don W.

PS. What is funny about the usage of that drug is that I squeeze out as
much moisture as possible from the eye and then apply the drop. So that I
can get the maximum use out of a singular drop. One is advised not to
double drop since it tends to wash out the medication from the eye.
Interesting, I thought.





"ray" <spammers at (no spam) do.not.reply.com> wrote in message
news:hflm24hs4fqcgvk7llnc9aujlqun5c9iea at (no spam) 4ax.com...
Quote:
On Wed, 14 May 2008 12:56:02 -0700, "Don W" <dwilgus at (no spam) prodigy.net
wrote:

Thanks.

How might the cornea react to Xalantan with this kind of condition?


Also, is the morning "fuzziness" granular or just overall "fuzzy"? (If
that
is clear?).

For high contrast items such as point source of light or black print
on white background it is multiple images. In my case sometimes it is
as many as 6 images smeared vertically. For lower contrast it just
looks fuzzy. Removing excess water from the cornea with salt water or
a hair dryer improves vision. What is Xalantan?



Don W.




"Mike Tyner" <mtyner at (no spam) mindspring.com> wrote in message
news:BN6dnQqrkNPHO7rVnZ2dnUVZ_r6rnZ2d at (no spam) giganews.com...
The corneal stroma swells and loses transparency if water isn't actively
pumped out.

The endothelium contains the pump.

When the lids are closed overnight, oxygenation drops.

Healthy endothelium has enough reserve to keep the cornea clear
overnight.

-MT


"Don W" <dwilgus at (no spam) prodigy.net> wrote in message
news:AkNVj.3320$nW2.1546 at (no spam) nlpi064.nbdc.sbc.com...
Just exactly what causes the "morning fuzziness"?

Don W.


ray...
Posted: Wed May 14, 2008 6:10 pm
Guest
On Wed, 14 May 2008 15:06:53 -0700, "Don W" <dwilgus at (no spam) prodigy.net>
wrote:

Quote:
Interesting about too much fluid in the cornea. I always got the impression
the it was my cornea (outside) surface that needed a few blinks to become
more "optically smooth".

How far apart are your multiple images? Degrees, minutes? Those types of
multiple images I do not have.

A traffic stop light will have 2 red lights spaced the same distance
apart as the distance between amber and red. A cross road (black
cross on yellow sign) will have 2 black crosses bars with yellow in
between the thickness of a crossbar. From 10 feet a 1/8" green LED
will be a series of dots about an inch high. Normal text in a book
will have a readable ghost image 1/2 the height of text. I am getting
used to it.

My corneal pressure is 16, with 12 to 21 normal.

Quote:

Xalatan is a glaucoma drug that reduces eye pressure, namely the anterior
chamber (hopefully the posterior tracks), before higher pressure affects the
optic nerve, which affects blood flow to the eye. The drug, goes thru the
entire cornea (and that would include the endothelium). (As far as I
understand it -- no medical type).

Don W.

PS. What is funny about the usage of that drug is that I squeeze out as
much moisture as possible from the eye and then apply the drop. So that I
can get the maximum use out of a singular drop. One is advised not to
double drop since it tends to wash out the medication from the eye.
Interesting, I thought.





"ray" <spammers at (no spam) do.not.reply.com> wrote in message
news:hflm24hs4fqcgvk7llnc9aujlqun5c9iea at (no spam) 4ax.com...
On Wed, 14 May 2008 12:56:02 -0700, "Don W" <dwilgus at (no spam) prodigy.net
wrote:

Thanks.

How might the cornea react to Xalantan with this kind of condition?


Also, is the morning "fuzziness" granular or just overall "fuzzy"? (If
that
is clear?).

For high contrast items such as point source of light or black print
on white background it is multiple images. In my case sometimes it is
as many as 6 images smeared vertically. For lower contrast it just
looks fuzzy. Removing excess water from the cornea with salt water or
a hair dryer improves vision. What is Xalantan?



Don W.




"Mike Tyner" <mtyner at (no spam) mindspring.com> wrote in message
news:BN6dnQqrkNPHO7rVnZ2dnUVZ_r6rnZ2d at (no spam) giganews.com...
The corneal stroma swells and loses transparency if water isn't actively
pumped out.

The endothelium contains the pump.

When the lids are closed overnight, oxygenation drops.

Healthy endothelium has enough reserve to keep the cornea clear
overnight.

-MT


"Don W" <dwilgus at (no spam) prodigy.net> wrote in message
news:AkNVj.3320$nW2.1546 at (no spam) nlpi064.nbdc.sbc.com...
Just exactly what causes the "morning fuzziness"?

Don W.



Don W...
Posted: Wed May 14, 2008 9:04 pm
Guest
Quote:
multiple images I do not have.

A traffic stop light will have 2 red lights spaced the same distance
apart as the distance between amber and red. A cross road (black
cross on yellow sign) will have 2 black crosses bars with yellow in
between the thickness of a crossbar. From 10 feet a 1/8" green LED
will be a series of dots about an inch high. Normal text in a book
will have a readable ghost image 1/2 the height of text. I am getting
used to it.

My corneal pressure is 16, with 12 to 21 normal.

For a "standard E" (20/20 vision) the subtended angle is 5 minutes or 0.083
degree. Your 1 inch at 10 feet is 0.48 degree. These are remarkable
offsets. All caused by deformations in the cornea? (Or in the lens??).
Seems like they should be able to nail down the cause.

Don W.
Mike Tyner...
Posted: Wed May 14, 2008 10:47 pm
Guest
"Don W" <dwilgus at (no spam) prodigy.net> wrote

Quote:
degree. Your 1 inch at 10 feet is 0.48 degree. These are remarkable
offsets. All caused by deformations in the cornea? (Or in the lens??).
Seems like they should be able to nail down the cause.

It isn't considered useful, because it wouldn't alter the treatment.

If the diplopia is lenticular (my vote), his acuity is apparently still too
good to expect insurance to cover cataract surgery.

If it's corneal, rigid contact lenses would eliminate the diplopia but he
probably wouldn't like wearing rigid contacts and no surgeon wants to
recommend contacts to a presbyope with symptomatic Fuchs.

It would take about two minutes to numb his cornea, pop on a rigid contact
lens and prove the origin of the diplopia. But that's not so easy to justify
if you have to buy (design, order, wait for) a gas perm contact lens just
for a one-shot diagnostic fit.

They say "it's academic" meaning "it ain't worth the trouble."

-MT
John Hasenkam...
Posted: Thu May 15, 2008 10:49 am
Guest
This is a long shot Ray and may not work for you but I had a very similiar
vision problem for a number of years. Vertical dipoplia Quite by accident I
found that wearing a sleep mask basically eliminated the problem. I have no
idea why this worked except to suggest that because I have a orbit
deformation(depressed bone) on the side of my good eye, when sleeping my
cornea is
subject to pressure from the pillow and the mask relieves this. It would
take about an hour each morning for this vision problem to recede, until I
used the sleep mask.

I repeat: it's a long shot and it took a number of weeks for the vision to
stabilise. Cheap and good for your sleep anyway so try it. I can't even say
with certainty that the sleep mask made the difference but I did go without
the sleep mask for a few weeks and the problem returned so I am loathe to
try that little experiment again.

PS: same problem as you, saw a number of doctors who offered no solution or
diagnosis.

Mike T., if you would be so kind, I would appreciate your opinion on this
wild idea!

"ray" <spammers at (no spam) do.not.reply.com> wrote in message
news:nifo24tr0orbhlfduttg76a42ld9k33nn0 at (no spam) 4ax.com...
Quote:
On Wed, 14 May 2008 19:04:44 -0700, "Don W" <dwilgus at (no spam) prodigy.net
wrote:

multiple images I do not have.

A traffic stop light will have 2 red lights spaced the same distance
apart as the distance between amber and red. A cross road (black
cross on yellow sign) will have 2 black crosses bars with yellow in
between the thickness of a crossbar. From 10 feet a 1/8" green LED
will be a series of dots about an inch high. Normal text in a book
will have a readable ghost image 1/2 the height of text. I am getting
used to it.

My corneal pressure is 16, with 12 to 21 normal.

For a "standard E" (20/20 vision) the subtended angle is 5 minutes or
0.083
degree. Your 1 inch at 10 feet is 0.48 degree. These are remarkable
offsets. All caused by deformations in the cornea? (Or in the lens??).
Seems like they should be able to nail down the cause.

Don W.


You are talking about medical people. I have read on the average it
takes 6 diagnosis to get it right. That was how many it took to find
a torn rotator cuff in my arm. For my vision the first doctor said
cataracts, the second said wrong glasses, the third said Fuch's. They
all used the same examination procedure. Others with Fuch's have said
it took more than 6 doctors to find it. I think it highly likely that
I have Fuch's as the major problem and cataracts. I am not sure that
with my symptoms that it is a complete explanation. The vision is not
as bad as the numbers would suggest because the distortion is only
vertical, the vision waxes and wanes and what I described it when it
is at its worst.
Don W...
Posted: Thu May 15, 2008 12:52 pm
Guest
How would Fuchs' and the use of Xalatan (to lower IOP) go together?

Complement or complicate the situation??

Don W.
Mike Tyner...
Posted: Thu May 15, 2008 1:53 pm
Guest
"John Hasenkam" <johnh at (no spam) goawayplease.com> wrote

Quote:
Mike T., if you would be so kind, I would appreciate your opinion on this
wild idea!

You didn't say specifically that your diplopia was monocular. If that's what
you mean then yes, it's certainly reasonable to try a sleep mask.

Monocular diplopia can arise from the cornea, where dips and peaks form
images that aren't exactly coaxial. It can also arise from the lens, where
wedge-shaped areas degrade and their refractive index changes and those
areas start to form independent images.

As you might imagine, in the first case, corneal molding and surface
distortions could be affected by a sleep mask. In the second case, changing
the cornea will have no real effect.

Fuch's dystrophy doesn't usually cause topographical changes in the cornea
without real pain. Ray hasn't described any pain and AFAIK has never had
corneal erosions.

That, and his age, lead me to suspect that his diplopia is lenticular. If he
put on a gas-perm contact lens and the diplopia remained, we could be sure
that it's lenticular and would be "cured" by cataract surgery. OTOH, if it's
corneal, it will disappear with a rigid contact lens. This isn't worth the
trouble unless they're considering surgery or other major treatment.

-MT

Quote:

"ray" <spammers at (no spam) do.not.reply.com> wrote in message
news:nifo24tr0orbhlfduttg76a42ld9k33nn0 at (no spam) 4ax.com...
On Wed, 14 May 2008 19:04:44 -0700, "Don W" <dwilgus at (no spam) prodigy.net
wrote:

multiple images I do not have.

A traffic stop light will have 2 red lights spaced the same distance
apart as the distance between amber and red. A cross road (black
cross on yellow sign) will have 2 black crosses bars with yellow in
between the thickness of a crossbar. From 10 feet a 1/8" green LED
will be a series of dots about an inch high. Normal text in a book
will have a readable ghost image 1/2 the height of text. I am getting
used to it.

My corneal pressure is 16, with 12 to 21 normal.

For a "standard E" (20/20 vision) the subtended angle is 5 minutes or
0.083
degree. Your 1 inch at 10 feet is 0.48 degree. These are remarkable
offsets. All caused by deformations in the cornea? (Or in the lens??).
Seems like they should be able to nail down the cause.

Don W.


You are talking about medical people. I have read on the average it
takes 6 diagnosis to get it right. That was how many it took to find
a torn rotator cuff in my arm. For my vision the first doctor said
cataracts, the second said wrong glasses, the third said Fuch's. They
all used the same examination procedure. Others with Fuch's have said
it took more than 6 doctors to find it. I think it highly likely that
I have Fuch's as the major problem and cataracts. I am not sure that
with my symptoms that it is a complete explanation. The vision is not
as bad as the numbers would suggest because the distortion is only
vertical, the vision waxes and wanes and what I described it when it
is at its worst.


 
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