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Science Forum Index » Bio Evolution Forum » Genomic Instability?
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Posted: Thu Feb 01, 2007 12:46 pm |
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I found the following interesting:
"If the damaged DNA is in one of the germ cells (egg or sperm) then
the DNA changes may be carried into the next generation. While many
plant and animal experiments leave no doubt that radiation exposure
can alter genetic material, we should note that this genetic effect
has not yet been observed in the case of the Hiroshima and Nagasaki
survivors. However this does not mean that there is no such effect in
humans. It may be that there were genetic abnormalities produced that
were incompatible with life and those pregnancies therefore ended in
miscarriage. It may also be that an increased rate of genetic
abnormalities will be found in future generations, that is, the
changes will skip one or more generations.
The phenomenon called genomic instability has been the subject of
research in recent years. This is the process whereby damage inflicted
on cells is detected only after several cell divisions. This
phenomenon has been reproduced several times in laboratory studies of
human cells but has not been confirmed in living humans. Such studies
would necessarily need to be extraordinarily long. However if the
theory of induced genetic instability is correct, then the human gene
pool could be permanently altered."
I'm convinced that before genetic engineering of humans can occur to
make them non-aggressive there will be at least one (if not more)
nuclear bombs detonated on civilian populations either by nuclear
terrorists (due largely to unsecured nuclear material) and/or by
states. Unlike Hoelzer I don't see this just as a current "snapshot in
time". Theoretically, the international environment could change but I
see no "forseeable" trends leading to non-proliferation and securing
nuclear materials, taking nuclear warhaeads off launch status, etc. Of
course, the biggest threat is between the U.S. and Russia which have
the majority of the nuclear arsenal but a nuclear terrorists could
trigger and inflame the international situation to the degree other
countries could become involved.
The hypothetical question I'm interested in is would a "widespread"
nuclear conflict (and this would need to be defined by the tonnage and
destructiveness of nuclear weapons detonated on civilian/military
centers) cause genomic instability of the human species?
Although according to this article germ cells were not damaged in
Hiroshima and Nagasaki these were small bombs compared with the
warheads today or the fissionable material located at nuclear sites.
Since animal experiments leave no doubt radiation exposure can alter
genetic material it seems a widespread nuclear event could damage the
germ cells in some way. Is this reasonable to assume? As the article
states, "It may also be that an increased rate of genetic
abnormalities will be found in future generations, that is, the
changes will skip one or more generations." The Japanese people? The
Marshallese people? Any info on this?
It goes on to say, "The phenomenon called genomic instability has been
the subject of research in recent years. This is the process whereby
damage inflicted on cells is detected only after several cell
divisions. This phenomenon has been reproduced several times in
laboratory studies of human cells but has not been confirmed in living
humans". I suppose if a big enough nuclear event does happen this will
provide existing scientists with a new "fruitful" area" of research.
Finally, it states "However if the theory of induced genetic
instability is correct, then the human gene pool could be permanently
altered". How? That is what I'm curious about. Are there any
geneticists with enough of a background in nuclear radiation to at
least hypothsize what the genetic consequences could be?
I've also read that those humans who survived a big nuclear event and
were able to reproduce would be a highly selectable minority. Assuming
that is the case what would this special population possess in terms
of genes to be able to survive and propagate? I'm assuming a nuclear
winter scenario here.
I have to assume the military has already come up with "contingency"
plans for various scenarios but I think there are some unanswered
scientific questions. Given the current climate it seems likely
martial law would be declared but with a country with this size
population it would seem likely there would be a scarcity of resources
to respond; witness Hurricane Katrina.
Of course there is North Korea, Pakistan and India and Iran. One saw
how the U.S. responded to 911; bombing Afghanistan and invading and
bombing Iraq and killing 100,000 women and children. What would be
their response if they found out a terrorist cell who detonated a
nuclear bomb in the U.S. was supported by a state? Likely they would
respond with nuclear weapons. This Administration has a record of when
something bad happens of making it worse.
Australia is a rich source of uranium.
Michael Ragland
Medical Association for Prevention of War, Australia
The health impacts of nuclear power
Nuclear Forum, UNSW, October 18, 2006
Dr Sue Wareham, Former President,
Medical Association for Prevention of War
"The health impacts of nuclear power" is not necessarily an easy topic
to talk on because it is an area of medicine where there are large
gaps in our knowledge. Our knowledge has been evolving over about a
century or more, and for most of this time it has been a controversial
area of medicine, significantly because powerful interests have
clashed with the need for open, transparent research.
After the discovery of strange rays emanating from a compound of
uranium in 1896, and hence the discovery of radioactivity, which
followed very closely the discovery of X-rays in 1895, scientists and
the medical community sought applications for these new and intriguing
phenomena. However it soon became apparent that there were hazards
associated with their use, especially the development of cancers.
It was in 1928 that the first recommended limits for radiation
exposure were set. Since that time these limits have been revised on a
number of occasions, and on each occasion they have been reduced. That
is, new knowledge on the biological effects of radiation exposure has
consistently raised further concerns about the effects of previously
accepted levels of exposure.
It would therefore be extremely foolish to regard our current state of
knowledge as final, and to accept currently accepted exposure levels
as guaranteeing safety. In fact exposure limits are not designed to
guarantee safety. They are set at a level that is said to reduce risk
to "acceptable" levels. This in itself is not necessarily a criticism.
Most human activities expose us to some risk. What is more worrying
however is the fact that the nuclear age is very young and decisions
we make now, with our deeply imperfect state of knowledge, may have
lasting adverse effects for an extremely long time.
Early understanding of radiation biology was that there was a
threshold below which radiation caused no harm. This threshold
hypothesis has largely been abandoned, and there is now near universal
agreement that there is no evidence of a threshold below which
radiation exposure poses no risk. The Committee on the Biological
Effects of Ionizing Radiation, which is a panel within the US National
Academy of Sciences, re-affirmed in its most recent statement in June
2005 that "the smallest dose has the potential to cause a small
increase in risk to humans".
In June 2005, the British Medical Journal published a review of the
risk of cancer after low doses of ionising radiation to workers in the
nuclear industry in 15 countries, and this showed a small excess risk
of cancer. While the fact that the risk from low level radiation
exposure may be small in any particular individual, when this risk is
translated across populations, the increase in numbers of cancers can
be considerable.
One of the factors that the nuclear industry frequently reminds us of
is the fact that we are all exposed to background radiation, from
cosmic rays from the sun, from outer space, from gamma radiation from
the ground and from building materials, and to the naturally occurring
isotopes, especially potassium, in our own bodies. In addition
radiation from the legacy of atmospheric nuclear tests, from luminous
watch dials and high-altitude flights add to our exposure, as do
medical tests involving X-rays or nuclear medicine scans that many of
us undergo. What the industry does not tell us is that there is no
evidence that any of these things, including background radiation, are
perfectly safe. Almost certainly they contribute to cancer in our
society regardless of additional radiation from the nuclear power
industry.
It is well accepted in medicine that tests involving ionising
radiation should not be done unless the expected benefit outweighs the
risk of low-level radiation exposure. This is not a controversial
aspect of medicine. It is core, mainstream medical practice. It is
also unquestioned that X-rays are not done early in pregnancy when the
foetus is forming, and generally not in late pregnancy either, because
the risk to the foetus from X-rays is well known and accepted. We know
that children are more sensitive to the effects of radiation than
adults, and females are more sensitive than males.
How does ionising radiation affect health ?
Radiation exposure involves the transfer of energy to bodily tissues,
and this energy can harm or destroy molecules in human and other
animal cells. If the dose of radiation is sufficiently high, such as
that received by some of the liquidators at Chernobyl and by many of
the victims at Hiroshima and Nagasaki, then acute radiation sickness
will result, with predictable results that can be fatal depending on
the dose.
If the dose of radiation is low, however, the situation is less clear-
cut. Often the damage done to a cell is not clinically important. But
if the damage is to a molecule of DNA, which carries the cell's
genetic code, then the cell may fail to reproduce, or the DNA might
successfully repair itself, or the cell might survive with impaired
DNA, that is a mutation, which in turn can result in cancer many years
later. Cancer can be initiated by a single radiation track through a
single cell nucleus; hence the belief that the lowest possible dose of
radiation can be harmful. While the probability of a cancer developing
increases with the radiation dose, it is a random effect. It may or
may not occur.
If the damaged DNA is in one of the germ cells (egg or sperm) then the
DNA changes may be carried into the next generation. While many plant
and animal experiments leave no doubt that radiation exposure can
alter genetic material, we should note that this genetic effect has
not yet been observed in the case of the Hiroshima and Nagasaki
survivors. However this does not mean that there is no such effect in
humans. It may be that there were genetic abnormalities produced that
were incompatible with life and those pregnancies therefore ended in
miscarriage. It may also be that an increased rate of genetic
abnormalities will be found in future generations, that is, the
changes will skip one or more generations.
The phenomenon called genomic instability has been the subject of
research in recent years. This is the process whereby damage inflicted
on cells is detected only after several cell divisions. This
phenomenon has been reproduced several times in laboratory studies of
human cells but has not been confirmed in living humans. Such studies
would necessarily need to be extraordinarily long. However if the
theory of induced genetic instability is correct, then the human gene
pool could be permanently altered.
It has long been observed that children whose fathers worked at the
Sellafield reprocessing plant in the UK have an increased risk of
developing childhood leukemia. Leukemia clusters near other nuclear
establishments have been noted also. Originally this was thought to
possibly relate to local environmental contamination, but a report
published in the British Medical Journal in 1990, by Gardner,
suggested another possible explanation - that radiation affected the
father's sperm producing a mutation that increased the risk of
childhood leukemia. Again, we do not have definite proof of this.
There are many other uncertainties in the field of radiation biology,
including the extent to which data from an acute (sudden) high dose
exposure such as that at Hiroshima can be applied to chronic (long
term) low dose exposure (such as exposures associated with the nuclear
power industry).
Difficulties have been compounded by the secrecy that has surrounded
all matters related to nuclear power and nuclear weapons. In the US,
for example, the Dept of Energy has consistently suppressed
information in relation to the health of workers in the nuclear
weapons industry. Tactics include the refusal to release data on
exposure levels, and the loss of funding for researchers whose
findings are unfavourable.
Probably the most difficult factor to overcome in demonstrating the
health effects of radiation exposure is the long lead times involved
between exposure and outcomes such as cancer. Often this is decades.
For example the cancers formed as a result of the A-bombs dropped on
Hiroshima and Nagasaki have not yet reached their peak. The difficulty
is magnified by the fact that there is no way of distinguishing a
cancer formed as a result of radiation from any other cancer.
Therefore to link a particular cancer to a particular exposure is
generally impossible. We must rely on very large and very expensive
epidemiological studies which must address multiple confounding
factors. The lower the dose, the larger the study group needs to be.
This fact has been used unscrupulously by the nuclear industry. We
should observe the language used by the industry - for example, words
such as cancers "proven" or "definitely linked' with Chernobyl or
other accidents. The industry knows that proving such a link is
impossible.
So that's some of the background to this subject and some of the
difficulties faced by researchers in the area. But how do we apply
this, and what is the evidence that seems most pertinent to Australia
right now as our government drives an agenda to dig up as much uranium
as possible and sell it to almost anyone ?
Uranium mining
Uranium-rich pitchblende has been mined for centuries. Early in the
19th century doctors in Czechoslovakia noticed that miners were dying
early from a lung condition they called "mountain sickness". The
sickness was of course lung cancer, which has been, and remains, a
significant risk for uranium miners at practically all places where
uranium has been mined, including Germany, Czechoslovakia, USA,
Canada, and France. In Australia, the numbers available for study are
small, but data from Radium Hill support the finding of an increased
rate of lung cancer. The risk is dose-related, and there is no
evidence of a threshold below which there is no risk.
In 1983, the US Nuclear Regulatory Commission (NRC) stated that the
wastes from uranium mining were the most ecologically damaging wastes
produced in the whole nuclear fuel chain. The NRC cited 3 main areas
of concern: firstly the enormous volumes of waste (tailings) produced
by uranium mining and milling; secondly, the radioactivity contained
in this waste; and thirdly, the prolonged life (thousands of years) of
the waste.
Uranium tailings contain over 85% of the radioactivity of the original
ore, primarily in the form of radium-226 (which has a half life of
1,600 years) and thorium-230 (half life 75,400 years). Radium and
other decay products attach themselves to tiny particles of dust and
smoke which can then be inhaled or ingested by miners and others in
the vicinity. Radium can also be concentrated in the food chain.
The most significant decay product of radium is radon gas, a short-
lived (half life 3.8 days) radioactive gas which is released when
uranium ore is mined. Radon and its decay products can be distributed
over large distances, depending on weather conditions, and, when
inhaled, deposit in the bronchial walls in the lungs.
In addition, uranium ore emits gamma radiation continuously, so that
uranium miners are exposed to both external radiation from gamma rays,
and internal radiation from inhaled radon and other alpha-emitting
particles.
In relation to other health effects from uranium mining, a study
published in 1992 examined birth data for over 13,000 Navajo children
born between 1964 and 1981 in Shiprock, New Mexico, in a region where
there are many tailings dumps. The study reported a statistically
significant increase in birth defects, stillbirths and illnesses
during infancy.
Nuclear Accidents
One of the most feared events associated with nuclear power is a loss
of coolant accident and melt-down as occurred at Chernobyl, with
widespread dispersion of radioactivity. We should remember that a
nuclear reactor houses vastly greater quantities of radioactivity than
that released in a nuclear weapon explosion.
The major radioisotopes present in a nuclear reactor core that are of
biological significance include caesium-137 (which mimics potassium
and is deposited in muscle), strontium-90 (which mimics calcium and is
therefore deposited mostly in bone), plutonium, and iodine-131. Iodine
is dominant in the first few weeks, and contaminates grass, and thence
cow's milk. After ingestion, it concentrates in the thyroid. After
Chernobyl, there was an unequivocal marked rise in the incidence of
thyroid cancer in the region. Caesium-137 exposes people both
externally, with gamma radiation from the ground which will last for
centuries, and internally through contaminated soil, vegetation and
food - primarily milk but also meat, fish and cereals.
Well, what do we know about the death toll from Chernobyl ? I'm going
to answer this mostly by reference to the UN Chernobyl Forum report
that was released in September 2005 by several UN agencies - including
the IAEA, the WHO and UNDP. The press release for the report in fact
reads as little more than a whitewash, and yet even the press release
gave an estimate of 4,000 excess Chernobyl-related deaths - far more
than the absurd figure of 40-50 deaths that we hear so often.
However the report itself gives a very different picture about
Chernobyl mortality from the press release. It lists predicted excess
cancer deaths among the different exposed populations (liquidators and
evacuees from different areas) but does not actually quote the total
of these deaths. If you do the sums yourself, it is 8,930 - a much
higher figure than the 4,000 in the press release.
However the report does not mention that the data exclude:
at least 600,000 of the liquidators (it includes figures for 200,000
only),
any consideration of health effects outside the Ukraine, Belarus and
Russia,
those born since 1986 and those yet to be born, and
any non-cancer effects.
These are all very glaring omissions.
Calculations that extrapolate from the Chernobyl Forum figures but
also include very conservative estimates for the above categories (but
not non-cancer effects other than in liquidators) give an estimate of
34,200-38,500 deaths. This also is likely to be an underestimate.
The Chernobyl Forum report totally ignores data from the Belarus
national cancer registry, despite the fact that these data were
published almost a year before the UN Chernobyl Forum report. The data
show an increase in cancer incidence, averaging 40%, in all regions,
most pronounced in the most heavily contaminated regions.
Reports from other sources have noted that infant leukemia rates in a
number of countries (including Greece and former West Germany) have
increased since Chernobyl, and that cancer incidence across Northern
Sweden has increased. Remember that the minimum latency period for
most solid cancers is at least 10-15 years, generally much longer, and
that most cancers that are or will be attributable to Chernobyl are
yet to occur.
In brief, we will never know the total death toll from Chernobyl, but
we can confidently state that it will be at the very least in the tens
of thousands if not much higher.
We should note here also the very low-key role played by the WHO in
relation to radiation health matters. Since 1959 there has been an
agreement between the WHO and the IAEA, which stipulates that the WHO
will defer to the IAEA in matters related to radiation health. In
other words, the WHO has lost its scientific independence on the
health impacts of nuclear power and is not a credible authority on
these matters.
In relation to the 1979 accident at Three Mile Island in Pennsylvania,
USA, we are told by the nuclear industry that the health effects were
either non-existent or negligible. However others disagree. 1,400
local people took a class action against the operators of the plant
alleging adverse health effects including severe congenital
malformations. However the judge dismissed the experts who were going
to testify in the case and then claimed that there was no evidence to
present to the jury. There was a settlement which included the
stipulation that there be no publicity given to the claims.
I'll mention only very briefly the matter of nuclear waste. Good
epidemiological data on the health impacts of exposure to various
levels of nuclear waste are lacking. As mentioned earlier, studies to
provide such data would be extraordinarily difficult to implement and
extremely large in scale and long in duration. We can only extrapolate
from what we do know about the effects of radiation exposure. In
addition we do know that not a single country has in place a
satisfactory long term nuclear waste disposal plan. Therefore the
first priority, as with any intractable problem, is prevention. We
must stop adding to the problem by creating more nuclear waste.
It is worth noting that as new knowledge becomes available on the
issue of nuclear waste, the dangers appear even greater. For example,
in January 2000 the publication "Science" reported that plutonium
reacts differently from previously believed and, when exposed to air
and water, over time becomes very soluble in water. This has obvious
implications for underground disposal of waste.
The final issue that must be mentioned in relation to the health
effects associated with nuclear power is the inextricable links with
nuclear weapons - not just the proliferation of these weapons, but the
very existence of 27,000 of them, the world's most destructive and
terrifying weapons. There is no doubt that the development of nuclear
weapons in a number of countries has been aided by so-called peaceful
nuclear technology, as others at this conference have discussed. I
will simply add that of all the unresolved threats to human health,
nuclear weapons remains undoubtedly one of the greatest and the most
urgent. |
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| g |
Posted: Sun Feb 04, 2007 10:18 am |
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Guest
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Ragland,
I have an issue with the gross inconsistency of the MANY DIVERSE
rationales that have been tendered by many "experts" each speaking as though
from a cloud above -- if not Mt. Olympus, then certainly -- above the heads
of the ignorant masses of non-experts.
By 1900 there was a wide concensus among many fields of scientific inquiry
and speculation that there was a fundamental flaw in Darwin's concept of
natural selection, which was the SAME flaw in Lamarck's concept of
transmission of acquired characteristics; which was the SAME flaw in Herbert
Spencer's notion of "survival of the fittest," which... you get the idea...
was:
NONE OF THEM HAD COME UP WITH THE MECHANISM OR MECHANISMS PER
SE.
You and I know that Darwin kept REVISING his "Origin of the Species" in an
effort to "adapt" it to the objections of his peers. And historians who
have read the eleven or so REVISIONS have observed that, with each and every
rewrite his ideas became more, and more and more and more... guess what...
LAMARCKIAN.
When Mendel's work got resurrected (roughly a half century after it first
came out), as a result of its being perceived by an increasing number of
theorists and critics to offer the missing "mechanism," that (if I've got it
right from my reading) was what enabled the New Darwinian Synthesis (also
called Neo-Darwinism). And some historians (if I've got this right)
indicate that up to then there was a wide split between the preference among
many leading biologists for the classical Darwinian view of "natural
selection" and the paleontologists' preference for a more Lamarckian view.
Putting it very succinctly (hence in risk of distortion by simplistication)
paleontologists and biologists had a new synthesis which both could see some
possible sense in.
Today, if we were to say that *THE MECHANISM WHEREBY NATURAL SELECTION
TRANSPIRES* is clear and present and of a sufficient degree of detailed
verification to be termed a "law" (in the scientific sense) that would be AT
VERY BEST premature... and, at WORST, it would be presumptious and could
turn out to be untenable somewhere downstream from today.
This old layman has said it before and shall say it again, "Science is NOT
dogma. And deciples of a dogma, no matter how many experts might subscribe
to it, is not "top rate" science.
The angrier any entrenched advocate gets upon being accused of bias, the
more this old layman is reminded of the saying among political analysits
that, "When they say it's not about the money... it's about the money." I
use that analogy not because money is at issue (at least not in every
instance) but because certain GROUP CONSENSUSES as to the claiming of one
school of thought asserting their favorite presumptions against members of
members of another veritable cult of opinion, impress this old coot as more
of a "shouting match" and less of an actual search for answers... which is
what I would guess that "top rate" science should be about. And the
comparison is that when someone says it's not about a grouping of members of
a common opinion, that very well might be EXACTLY what it is about.
What ever happened to "I don't know.. but I'll tell you what I THINK," and
without opponents trying to enshrine their "opinion" in an ivory ego temple,
and put it on a pedestal.
If it were simple, obvious, and confirmed in minute detail, then there would
not BE any debate. And a many a person would not have to be called "stupid"
or "intransigent" or some such derogatory nomenclature for not bowing his
head in abject subjection.
If someone is going to point to a human and tell me that natural selection
by way of selfish genes made him smart enough to out-survive other critters,
then that person should not mind my asking, why the same did not happen to,
say, opossums. I read in a publication for game biologists that the very
most essential characteristic of Opossum Virginialis' which most accounts
for its adaptation to multiple geographical areas and invironments is the
fact that it is too stupid to get into habitat and food source ruts. More
specifically, the article informs that the cerebral cavity of a Virginia
Opossum, by comparison to other species indicates that it is "playing with
only about two-thirds of a deck."
So what have we here. Smart out-survives dumb for humans; but dumb
out-survives smart for opossums.
Oh, the rationalizing might go, I'm not looking at the WHOLE picture. What
works for an opossum works for the niche or niches they fill, but does not
work for the niche or niches humans fill. Get the picture. If one STARTS
OUT with the presumption that natural selection works because of
competition, then the way you PROVE that is by coming up with a
rationalization for why hot is cold and black is white and smart pays when
it pays and dumb pays when it pays...
If a scientist speaks of gradualism, and points to many species that have
changed gradually, and cites that to be a product of mutations, even during
times when geography, that is fine so far as it goes. But let him NOT OMIT
telling me how rhinoceroses were, by comparison, less vulnerable to
gradualism.
I'll stop. There are far too many rationalizations built upon
rationalizations built upon rationalizations for this poor old man to keep
up with... except to observe that as gaps appear in one's hypothesization,
if he is totally committed to it, all that is necessary is to beg the
presumption and gerrymander an explanation as to how it applies to the
"seeming" exception.
g |
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Posted: Sun Feb 04, 2007 10:19 am |
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On Feb 1, 2:46�pm, RAGLANDMYC...@AOL.COM wrote:
Quote: I found the following interesting:
"If the damaged DNA is in one of the germ cells (egg or sperm) then
the DNA changes may be carried into the next generation. While many
plant and animal experiments leave no doubt that radiation exposure
can alter genetic material, we should note that this genetic effect
has not yet been observed in the case of the Hiroshima and Nagasaki
survivors. However this does not mean that there is no such effect in
humans. It may be that there were genetic abnormalities produced that
were incompatible with life and those pregnancies therefore ended in
miscarriage. It may also be that an increased rate of genetic
abnormalities will be found in future generations, that is, the
changes will skip one or more generations.
The phenomenon called genomic instability has been the subject of
research in recent years. This is the process whereby damage inflicted
on cells is detected only after several cell divisions. This
phenomenon has been reproduced several times in laboratory studies of
human cells but has not been confirmed in living humans. Such studies
would necessarily need to be extraordinarily long. However if the
theory of induced genetic instability is correct, then the human gene
pool could be permanently altered."
I'm convinced that before genetic engineering of humans can occur to
make them non-aggressive there will be at least one (if not more)
nuclear bombs detonated on civilian populations either by nuclear
terrorists (due largely to unsecured nuclear material) and/or by
states. Unlike Hoelzer I don't see this just as a current "snapshot in
time". Theoretically, the international environment could change but I
see no "forseeable" trends leading to non-proliferation and securing
nuclear materials, taking nuclear warhaeads off launch status, etc. Of
course, the biggest threat is between the U.S. and Russia which have
the majority of the nuclear arsenal but a nuclear terrorists could
trigger and inflame the international situation to the degree other
countries could become involved.
The hypothetical question I'm interested in is would a "widespread"
nuclear conflict (and this would need to be defined by the tonnage and
destructiveness of nuclear weapons detonated on civilian/military
centers) cause genomic instability of the human species?
Although according to this article germ cells were not damaged in
Hiroshima and Nagasaki these were small bombs compared with the
warheads today or the fissionable material located at nuclear sites.
Since animal experiments leave no doubt radiation exposure can alter
genetic material it seems a widespread nuclear event could damage the
germ cells in some way. Is this reasonable to assume? As the article
states, "It may also be that an increased rate of genetic
abnormalities will be found in future generations, that is, the
changes will skip one or more generations." The Japanese people? The
Marshallese people? Any info on this?
It goes on to say, "The phenomenon called genomic instability has been
the subject of research in recent years. This is the process whereby
damage inflicted on cells is detected only after several cell
divisions. This phenomenon has been reproduced several times in
laboratory studies of human cells but has not been confirmed in living
humans". I suppose if a big enough nuclear event does happen this will
provide existing scientists with a new "fruitful" area" of research.
Finally, it states "However if the theory of induced genetic
instability is correct, then the human gene pool could be permanently
altered". How? That is what I'm curious about. Are there any
geneticists with enough of a background in nuclear radiation to at
least hypothsize what the genetic consequences could be?
I've also read that those humans who survived a big nuclear event and
were able to reproduce would be a highly selectable minority. Assuming
that is the case what would this special population possess in terms
of genes to be able to survive and propagate? I'm assuming a nuclear
winter scenario here.
I have to assume the military has already come up with "contingency"
plans for various scenarios but I think there are some unanswered
scientific questions. Given the current climate it seems likely
martial law would be declared but with a country with this size
population it would seem likely there would be a scarcity of resources
to respond; witness Hurricane Katrina.
Of course there is North Korea, Pakistan and India and Iran. One saw
how the U.S. responded to 911; bombing Afghanistan and invading and
bombing Iraq and killing 100,000 women and children. What would be
their response if they found out a terrorist cell who detonated a
nuclear bomb in the U.S. was supported by a state? Likely they would
respond with nuclear weapons. This Administration has a record of when
something bad happens of making it worse.
Australia is a rich source of uranium.
Michael Ragland
Medical Association for Prevention of War, Australia
The health impacts of nuclear power
Nuclear Forum, UNSW, October 18, 2006
Dr Sue Wareham, Former President,
Medical Association for Prevention of War
"The health impacts of nuclear power" is not necessarily an easy topic
to talk on because it is an area of medicine where there are large
gaps in our knowledge. Our knowledge has been evolving over about a
century or more, and for most of this time it has been a controversial
area of medicine, significantly because powerful interests have
clashed with the need for open, transparent research.
After the discovery of strange rays emanating from a compound of
uranium in 1896, and hence the discovery of radioactivity, which
followed very closely the discovery of X-rays in 1895, scientists and
the medical community sought applications for these new and intriguing
phenomena. However it soon became apparent that there were hazards
associated with their use, especially the development of cancers.
It was in 1928 that the first recommended limits for radiation
exposure were set. Since that time these limits have been revised on a
number of occasions, and on each occasion they have been reduced. That
is, new knowledge on the biological effects of radiation exposure has
consistently raised further concerns about the effects of previously
accepted levels of exposure.
It would therefore be extremely foolish to regard our current state of
knowledge as final, and to accept currently accepted exposure levels
as guaranteeing safety. In fact exposure limits are not designed to
guarantee safety. They are set at a level that is said to reduce risk
to "acceptable" levels. This in itself is not necessarily a criticism.
Most human activities expose us to some risk. What is more worrying
however is the fact that the nuclear age is very young and decisions
we make now, with our deeply imperfect state of knowledge, may have
lasting adverse effects for an extremely long time.
Early understanding of radiation biology was that there was a
threshold below which radiation caused no harm. This threshold
hypothesis has largely been abandoned, and there is now near universal
agreement that there is no evidence of a threshold below which
radiation exposure poses no risk. The Committee on the Biological
Effects of Ionizing Radiation, which is a panel within the US National
Academy of Sciences, re-affirmed in its most recent statement in June
2005 that "the smallest dose has the potential to cause a small
increase in risk to humans".
In June 2005, the British Medical Journal published a review of the
risk of cancer after low doses of ionising radiation to workers in the
nuclear industry in 15 countries, and this showed a small excess risk
of cancer. While the fact that the risk from low level radiation
exposure may be small in any particular individual, when this risk is
translated across populations, the increase in numbers of cancers can
be considerable.
One of the factors that the nuclear industry frequently reminds us of
is the fact that we are all exposed to background radiation, from
cosmic rays from the sun, from outer space, from gamma radiation from
the ground and from building materials, and to the naturally occurring
isotopes, especially potassium, in our own bodies. In addition
radiation from the legacy of atmospheric nuclear tests, from luminous
watch dials and high-altitude flights add to our exposure, as do
medical tests involving X-rays or nuclear medicine scans that many of
us undergo. What the industry does not tell us is that there is no
evidence that any of these things, including background radiation, are
perfectly safe. Almost certainly they contribute to cancer in our
society regardless of additional radiation from the nuclear power
industry.
It is well accepted in medicine that tests involving ionising
radiation should not be done unless the expected benefit outweighs the
risk of low-level radiation exposure. This is not a controversial
aspect of medicine. It is core, mainstream medical practice. It is
also unquestioned that X-rays are not done early in pregnancy when the
foetus is forming, and generally not in late pregnancy either, because
the risk to the foetus from X-rays is well known and accepted. We know
that children are more sensitive to the effects of radiation than
adults, and females are more sensitive than males.
How does ionising radiation affect health ?
Radiation exposure involves the transfer of energy to bodily tissues,
and this energy can harm or destroy molecules in human and other
animal cells. If the dose of radiation is sufficiently high, such as
that received by some of the liquidators at Chernobyl and by many of
the victims at Hiroshima and Nagasaki, then acute radiation sickness
will result, with predictable results that can be fatal depending on
the dose.
If the dose of radiation is low, however, the situation is less clear-
cut. Often the damage done to a cell is not clinically important. But
if the damage is to a molecule of DNA, which carries the cell's
genetic code, then the cell may fail to reproduce, or the DNA might
successfully repair itself, or the cell might survive with impaired
DNA, that is a mutation, which in turn can result in cancer many years
later. Cancer can be initiated by a single radiation track through a
single cell nucleus; hence the belief that the lowest possible dose of
radiation can be harmful. While the probability of a cancer developing
increases with the radiation dose, it is a random effect. It may or
may not occur.
If the damaged DNA is in one of the germ cells (egg or sperm) then the
DNA changes may be carried into the next generation. While many plant
and animal experiments leave no doubt that radiation exposure can
alter genetic material, we should note that this genetic effect has
not yet been observed in the case of the Hiroshima and Nagasaki
survivors. However this does not mean that there is no such effect in
humans. It may be that there were genetic abnormalities produced that
were incompatible with life and those pregnancies therefore ended in
miscarriage. It may also be that an increased rate of genetic
abnormalities will be found in future generations, that is, the
changes will skip one or more generations.
The phenomenon called genomic instability has been the subject of
research in recent years. This is the process whereby damage inflicted
on cells is detected only after several cell divisions. This
phenomenon has been reproduced several times in laboratory studies of
human cells but has not been confirmed in living humans. Such studies
would necessarily need to be extraordinarily long. However if the
theory of induced genetic instability is correct, then the human gene
pool could be permanently altered.
It has long been observed that children whose fathers worked at the
Sellafield reprocessing plant in the UK have an increased risk of
developing childhood leukemia. Leukemia clusters near other nuclear
establishments have been noted also. Originally this was thought to
possibly relate to local environmental contamination, but a report
published in the British Medical Journal in 1990, by Gardner,
suggested another possible explanation - that radiation affected the
father's sperm producing a mutation that increased the risk of
childhood leukemia. Again, we do not have definite proof of this.
There are many other uncertainties in the field of radiation biology,
including the extent to which data from an acute (sudden) high dose
exposure such as that at Hiroshima can be applied to chronic (long
term) low dose exposure (such as exposures associated with the nuclear
power industry).
Difficulties have been compounded by the secrecy that has surrounded
all matters related to nuclear power and nuclear weapons. In the US,
for example, the Dept of Energy has consistently suppressed
information in relation to the health of workers in the nuclear
weapons industry. Tactics include the refusal to release data on
exposure levels, and the loss of funding for researchers whose
findings are unfavourable.
Probably the most difficult factor to overcome in demonstrating the
health effects of radiation exposure is the long lead times involved
between exposure and outcomes such as cancer. Often this is decades.
For example the cancers formed as a result of the A-bombs dropped on
Hiroshima and Nagasaki have not yet reached their peak. The difficulty
is magnified by the fact that there is no way of distinguishing a
cancer formed as a result of radiation from any other cancer.
Therefore to link a particular cancer to a particular exposure is
generally impossible. We must rely on very large and very expensive
epidemiological studies which must address multiple confounding
factors. The lower the dose, the larger the study group needs to be.
This fact has been used unscrupulously by the nuclear industry. We
should observe the language used by the industry - for example, words
such as cancers "proven" or "definitely linked' with Chernobyl or
other accidents. The industry knows that proving such a link is
impossible.
So that's some of the background to this subject and some of the
difficulties faced by researchers in the area. But how do we apply
this, and what is the evidence that seems most pertinent to Australia
right now as our government drives an agenda to dig up as much uranium
as possible and sell it to almost anyone ?
Uranium mining
Uranium-rich pitchblende has been mined for centuries. Early in the
19th century doctors in Czechoslovakia noticed that miners were dying
early from a lung condition they called "mountain sickness". The
sickness was of course lung cancer, which has been, and remains, a
significant risk for uranium miners at practically all places where
uranium has been mined, including Germany, Czechoslovakia, USA,
Canada, and France. In Australia, the numbers available for study are
small, but data from Radium Hill support the finding of an increased
rate of lung cancer. The risk is dose-related, and there is no
evidence of a threshold below which there is no risk.
In 1983, the US Nuclear Regulatory Commission (NRC) stated that the
wastes from uranium mining were the most ecologically damaging wastes
produced in the whole nuclear fuel chain. The NRC cited 3 main areas
of concern: firstly the enormous volumes of waste (tailings) produced
by uranium mining and milling; secondly, the radioactivity contained
in this waste; and thirdly, the prolonged life (thousands of years) of
the waste.
Uranium tailings contain over 85% of the radioactivity of the original
ore, primarily in the form of radium-226 (which has a half life of
1,600 years) and thorium-230 (half life 75,400 years). Radium and
other decay products attach themselves to tiny particles of dust and
smoke which can then be inhaled or ingested by miners and others in
the vicinity. Radium can also be concentrated in the food chain.
The most significant decay product of radium is radon gas, a short-
lived (half life 3.8 days) radioactive gas which is released when
uranium ore is mined. Radon and its decay products can be distributed
over large distances, depending on weather conditions, and, when
inhaled, deposit in the bronchial walls in the lungs.
In addition, uranium ore emits gamma radiation continuously, so that
uranium miners are exposed to both external radiation from gamma rays,
and internal radiation from inhaled radon and other alpha-emitting
particles.
In relation to other health effects from uranium mining, a study
published in 1992 examined birth data for over 13,000 Navajo children
born between 1964 and 1981 in Shiprock, New Mexico, in a region where
there are many tailings dumps. The study reported a statistically
significant increase in birth defects, stillbirths and illnesses
during infancy.
Nuclear Accidents
One of the most feared events associated with nuclear power is a loss
of coolant accident and melt-down as occurred at Chernobyl, with
widespread dispersion of radioactivity. We should remember that a
nuclear reactor houses vastly greater quantities of radioactivity than
that released in a nuclear weapon explosion.
The major radioisotopes present in a nuclear reactor core that are of
biological significance include caesium-137 (which mimics potassium
and is deposited in muscle), strontium-90 (which mimics calcium and is
therefore deposited mostly in bone), plutonium, and iodine-131. Iodine
is dominant in the first few weeks, and contaminates grass, and thence
cow's milk. After ingestion, it concentrates in the thyroid. After
Chernobyl, there was an unequivocal marked rise in the incidence of
thyroid cancer in the region. Caesium-137 exposes people both
externally, with gamma radiation from the ground which will last for
centuries, and internally through contaminated soil, vegetation and
food - primarily milk but also meat, fish and cereals.
Well, what do we know about the death toll from Chernobyl ? I'm going
to answer this mostly by reference to the UN Chernobyl Forum report
that was released in September 2005 by several UN agencies - including
the IAEA, the WHO and UNDP. The press release for the report in fact
reads as little more than a whitewash, and yet even the press release
gave an estimate of 4,000 excess Chernobyl-related deaths - far more
than the absurd figure of 40-50 deaths that we hear so often.
However the report itself gives a very different picture about
Chernobyl mortality from the press release. It lists predicted excess
cancer deaths among the different exposed populations (liquidators and
evacuees from different areas) but does not actually quote the total
of these deaths. If you do the sums yourself, it is 8,930 - a much
higher figure than the 4,000 in the press release.
However the report does not mention that the data exclude:
at least 600,000 of the liquidators (it includes figures for 200,000
only),
any consideration of health effects outside the Ukraine, Belarus and
Russia,
those born since 1986 and those yet to be born, and
any non-cancer effects.
These are all very glaring omissions.
Calculations that extrapolate from the Chernobyl Forum figures but
also include very conservative estimates for the above categories (but
not non-cancer effects other than in liquidators) give an estimate of
34,200-38,500 deaths. This also is likely to be an underestimate.
The Chernobyl Forum report totally ignores data from the Belarus
national cancer registry, despite the fact that these data were
published almost a year before the UN Chernobyl Forum report. The data
show an increase in cancer incidence, averaging 40%, in all regions,
most pronounced in the most heavily contaminated regions.
Reports from other sources have noted that infant leukemia rates in a
number of countries (including Greece and former West Germany) have
increased since Chernobyl, and that cancer incidence across Northern
Sweden has increased. Remember that the minimum latency period for
most solid cancers is at least 10-15 years, generally much longer, and
that most cancers that are or will be attributable to Chernobyl are
yet to occur.
In brief, we will never know the total death toll from Chernobyl, but
we can confidently state that it will be at the very least in the tens
of thousands if not much higher.
We should note here also the very low-key role played by the WHO in
relation to radiation health matters. Since 1959 there has been an
agreement between the WHO and the IAEA, which stipulates that the WHO
will defer to the IAEA in matters related to radiation health. In
other words, the WHO has lost its scientific independence on the
health impacts of nuclear power and is not a credible authority on
these matters.
In relation to the 1979 accident at Three Mile Island in Pennsylvania,
USA, we are told by the nuclear industry that the health effects were
either non-existent or negligible. However others disagree. 1,400
local people took a class action against the operators of the plant
alleging adverse health effects including severe congenital
malformations. However the judge dismissed the experts who were going
to testify in the case and then claimed that there was no evidence to
present to the jury. There was a settlement which included the
stipulation that there be no publicity given to the claims.
I'll mention only very briefly the matter of nuclear waste. Good
epidemiological data on the health impacts of exposure to various
levels of nuclear waste are lacking. As mentioned earlier, studies to
provide such data would be extraordinarily difficult to implement and
extremely large in scale and long in duration. We can only extrapolate
from what we do know about the effects of radiation exposure. In
addition we do know that not a single country has in place a
satisfactory long term nuclear waste disposal plan. Therefore the
first priority, as with any intractable problem, is prevention. We
must stop adding to the problem by creating more nuclear waste.
It is worth noting that as new knowledge becomes available on the
issue of nuclear waste, the dangers appear even greater. For example,
in January 2000 the publication "Science" reported that plutonium
reacts differently from previously believed and, when exposed to air
and water, over time becomes very soluble in water. This has obvious
implications for underground disposal of waste.
The final issue that must be mentioned in relation to the health
effects associated with nuclear power is the inextricable links with
nuclear weapons - not just the proliferation of these weapons, but the
very existence of 27,000 of them, the world's most destructive and
terrifying weapons. There is no doubt that the development of nuclear
weapons in a number of countries has been aided by so-called peaceful
nuclear technology, as others at this conference have discussed. I
will simply add that of all the unresolved threats to human health,
nuclear weapons remains undoubtedly one of the greatest and the most
urgent.
Hey I just watched the Illusionist. I'm happy. Seriously though what
would be the limited effects on the ecology and biology if a few
nuclear bombs were detonated on populations? Would we just see alot of
radiation death and cancers? What would be the effects on the
worldwide climate?
Michael |
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| g |
Posted: Sun Feb 04, 2007 10:19 am |
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Quote: If a scientist speaks of gradualism, and points to many species that have
changed gradually, and cites that to be a product of mutations, even
during times when geography, that is fine so far as it goes. But let him
NOT OMIT telling me how rhinoceroses were, by comparison, less vulnerable
to gradualism.
Ragland,
Let me expand a teensy bit on this point.
If I ask a deeply committed advocate of natural selection why there were
changes in the lengths of giraffe's necks over a lot of millinea, the
regurge response is that the giraffes kept needing longer necks to reach
foliage higher than other animals could reach.
If I ask a deeply committed advocate of natural selection why elephants are
so big and strong, ONE reason might be that it enables them to push over
trees to eat the leaves which otherwise only giraffes could reach. Or, more
often the reason given to why any animal is big and strong is because that
provided an advantage of other animals that are smaller and weaker.
Then, if I ask a deeply committed advocate of natural selection why
rhinoceroses have remained so near the same for (millions?) of years, then
the answer is likely to be, "Oh, that's simple. They were well adapted way
back then, and did not HAVE to adapt as much as giraffes and elephants.
Or, if I ask a deeply committed advocate of nature selection why there was a
LINEAR progression from Eocene horses fossils in what is now the western
U.S. with four toes in front and three in back to hooves, then the answer
may be something such as "because hooves were advantageous."
I DO NOT REFUTE any of this. What my stance is, as of this moment is
NOT WHETHER natural selection has taken place, but HOW.
And if the discoveries of genes and DNA and RNA explain it, great. But one
question that keeps nagging at my curiosity is this:
If mutations are random, then why do they EVER come up with mutations that
CAN be selected in the first place.
I need to think through the sub-questions that lead up to this one,
actually. But something about the assertion that just giving something a
name does not explain the nitty gritty details NECESSARY for it to mean
anything.
If a patient asks a doctor, "What is causing me to have this fever, malaise,
joint pain, anorexia, muscle pain, joint pain ...?"
The doctor says, "Influenza."
Patient says, "Oh."
So, if we ask why giraffes "changed" to having longer necks, while elephants
got larger and grew long tusks, and
rhinocerouses stayed the same, and someone says, "Natural Selection."
There is an important difference between an explanation's being "self
explanatory" and its being "self instantiating."
Natural selection surely makes sense in its abstract simplistic form.
"Well, you see you get these random mutations and the ones that work get
chosen, while the ones that don't result in inferiority, which results in
getting cancelled out of the gene pool. Simple as that."
"How?"
"Genetics."
"Now that we KNOW how to compute it, what are the statistical odds against
ANY BENEFICIAL mutation being come up with in a species that will have any
ADAPTIVE VALUE? One in ten. One in a hundred. One in a million?"
How can random mutations come up with a linear progression from four toes to
a hoof in front and three toes to a hoof in the back? When we think long
and hard about it, what were the odds of a whole SERIES of mutations coming
up with a hoof? Just random chance, huh?
What's wrong with that picture, until and unless we know EXACTLY why an
earthworm can have many times more genes than a human.
Now please do not think that were I am going with this is to any dogma,
theistic, pantheistic, magical, or any other.
I'm not. I am not offering an answer. I am only saying... how do we KNOW.
Natural Selection, as a model for describing some things that have occurred
in nature is POST HOC. It is taking a result and guessing up a model which
describes it, and giving that a name. (Darwin did a WONDERFUL job of
describing some aspects of what has happened, and giving that a "NAME.")
Doctors had names for things like "consumption" long before any microbe or
virus was discovered.
"Why am I losing weight, doc? Why am I getting weaker? Why do I cough all
the time?"
Doctor: "Consumption."
Patient: "Oh."
g |
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| Tim Tyler |
Posted: Mon Feb 05, 2007 6:55 am |
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g wrote:
Quote: If I ask a deeply committed advocate of natural selection why there were
changes in the lengths of giraffe's necks over a lot of millinea, the
regurge response is that the giraffes kept needing longer necks to reach
foliage higher than other animals could reach.
That was what Darwin thought. However more recent workers
have concluded that giraffes have long necks so they
can better club other giraffes over the head with them -
e.g.:
"Evolution of the Giraffe Neck Via Sexual Selection"
http://www1.pacific.edu/~e-buhals/GIRAFFE2.htm
--
__________
|im |yler http://timtyler.org/ tim@tt1lock.org Remove lock to reply. |
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Posted: Mon Feb 05, 2007 6:55 am |
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On Feb 4, 12:18�pm, "g" <gillaw...@earthlink.net> wrote:
Quote: Ragland,
I have an issue with the gross inconsistency of the MANY DIVERSE
rationales that have been tendered by many "experts" each speaking as though
from a cloud above -- if not Mt. Olympus, then certainly -- above the heads
of the ignorant masses of non-experts.
By 1900 there was a wide concensus among many fields of scientific inquiry
and speculation that there was a fundamental flaw in Darwin's concept of
natural selection, which was the SAME flaw in Lamarck's concept of
transmission of acquired characteristics; which was the SAME flaw in Herbert
Spencer's notion of "survival of the fittest," which... you get the idea...
was:
NONE OF THEM HAD COME UP WITH THE MECHANISM OR MECHANISMS PER
SE.
You and I know that Darwin kept REVISING his "Origin of the Species" in an
effort to "adapt" it to the objections of his peers. And historians who
have read the eleven or so REVISIONS have observed that, with each and every
rewrite his ideas became more, and more and more and more... guess what...
LAMARCKIAN.
When Mendel's work got resurrected (roughly a half century after it first
came out), as a result of its being perceived by an increasing number of
theorists and critics to offer the missing "mechanism," that (if I've got it
right from my reading) was what enabled the New Darwinian Synthesis (also
called Neo-Darwinism). And some historians (if I've got this right)
indicate that up to then there was a wide split between the preference among
many leading biologists for the classical Darwinian view of "natural
selection" and the paleontologists' preference for a more Lamarckian view.
Putting it very succinctly (hence in risk of distortion by simplistication)
paleontologists and biologists had a new synthesis which both could see some
possible sense in.
Today, if we were to say that *THE MECHANISM WHEREBY NATURAL SELECTION
TRANSPIRES* is clear and present and of a sufficient degree of detailed
verification to be termed a "law" (in the scientific sense) that would be AT
VERY BEST premature... and, at WORST, it would be presumptious and could
turn out to be untenable somewhere downstream from today.
This old layman has said it before and shall say it again, "Science is NOT
dogma. And deciples of a dogma, no matter how many experts might subscribe
to it, is not "top rate" science.
The angrier any entrenched advocate gets upon being accused of bias, the
more this old layman is reminded of the saying among political analysits
that, "When they say it's not about the money... it's about the money." I
use that analogy not because money is at issue (at least not in every
instance) but because certain GROUP CONSENSUSES as to the claiming of one
school of thought asserting their favorite presumptions against members of
members of another veritable cult of opinion, impress this old coot as more
of a "shouting match" and less of an actual search for answers... which is
what I would guess that "top rate" science should be about. And the
comparison is that when someone says it's not about a grouping of members of
a common opinion, that very well might be EXACTLY what it is about.
What ever happened to "I don't know.. but I'll tell you what I THINK," and
without opponents trying to enshrine their "opinion" in an ivory ego temple,
and put it on a pedestal.
If it were simple, obvious, and confirmed in minute detail, then there would
not BE any debate. And a many a person would not have to be called "stupid"
or "intransigent" or some such derogatory nomenclature for not bowing his
head in abject subjection.
If someone is going to point to a human and tell me that natural selection
by way of selfish genes made him smart enough to out-survive other critters,
then that person should not mind my asking, why the same did not happen to,
say, opossums. I read in a publication for game biologists that the very
most essential characteristic of Opossum Virginialis' which most accounts
for its adaptation to multiple geographical areas and invironments is the
fact that it is too stupid to get into habitat and food source ruts. More
specifically, the article informs that the cerebral cavity of a Virginia
Opossum, by comparison to other species indicates that it is "playing with
only about two-thirds of a deck."
So what have we here. Smart out-survives dumb for humans; but dumb
out-survives smart for opossums.
Oh, the rationalizing might go, I'm not looking at the WHOLE picture. What
works for an opossum works for the niche or niches they fill, but does not
work for the niche or niches humans fill. Get the picture. If one STARTS
OUT with the presumption that natural selection works because of
competition, then the way you PROVE that is by coming up with a
rationalization for why hot is cold and black is white and smart pays when
it pays and dumb pays when it pays...
If a scientist speaks of gradualism, and points to many species that have
changed gradually, and cites that to be a product of mutations, even during
times when geography, that is fine so far as it goes. But let him NOT OMIT
telling me how rhinoceroses were, by comparison, less vulnerable to
gradualism.
I'll stop. There are far too many rationalizations built upon
rationalizations built upon rationalizations for this poor old man to keep
up with... except to observe that as gaps appear in one's hypothesization,
if he is totally committed to it, all that is necessary is to beg the
presumption and gerrymander an explanation as to how it applies to the
"seeming" exception.
g
I just stated my opinion on the liklihood in the forseeable future of
a nuclear bomb being detonated on a population. Yes, it seems rather
arrogant to state I'm "convinced" this is going to happen. However,
even biologist Guy Hoelzer agreed if "present" trends continue it is a
likely hypothesis this will happen. He is open, however, to the
environment changing and man is an important part of this process. In
other words things could change which would make the liklihood of a
nuclear bomb being detonated on a population less likely.
However, considering the current proliferation outside the traditional
nuclear club of seven countries or so, nuclear smuggling and unsecured
nuclear material both in the U.S. and Russia (in Russia it is worse)
and international terrorist groups...I'm not encouraged.
As one scientist stated we all go extinct and people are more
concerned about their own mortality than that of a massive wipeout. I
think, however, its time for ordinary folks to start discussing the
after effects of a nuclear bomb being detonated. I admit this could
take many scenarios and no one knows what the the destructiveness of
the bomb(s) will be, where they will be detonated or how various
states will react to the event. IMO, it will result from a terrorist
cell. So why not discuss hypothetical scenarios? What would be the
most accessible and likely targets in the U.S.? The U.S. is generally
despised around the world. Even the show "24" on television makes its
drama from such scenarios. If the terrorists don't attack an unsecured
U.S. nuclear facility which already hypothetically has the material to
set off a chain reaction than it seems a port city would be likely
selected.
A full scale nuclear event would really refute Darwin since it would
result in the possible extinction of mankind.
I see in the cards, however, a "limited" nuclear event where most
countries are petrified and "stay out" of the mess. I see the U.S.
retaliating against the "sponsor" state of such a terrorist cell is
successful in detonating a nuclear bomb in the U.S. Besides the
horrible death toll on the targeted populace and the after effects of
the radiation I see another adverse effect on civil and human rights
and the dissolution of the U.S. Constitution. As retired General Tommy
Franks stated (and which he was widely censured for saying so) if
there is another terrorist attack then there will gradually come
Martial Law in the U.S.
But all of this is not related to my original question (which you
really did not answer but are free to email me) how this would effect
the biology and ecology of the earth. We are already in global
warming. Short of a nuclear winter what would be the effects of a
nuclear bomb(s) on the ecology and biosphere? Would it increase global
warming? I would think it would. I would think it would do damage to
the ecology of earth. I've read today's nuclear bombs are much more
deadlier than the ones dropped on Hiroshima and Nagasaki. Some of them
also are multiple warheads with biological and chemical weapons.
Genomic instability posited the worse case scenario and no one has
responded. I find it hard to believe no germ cell damage was done to
the Japanese, Marshallese and victims of Cherynobyl. Are germ cells
really that robust? Have any experiments been done on animals and is
there a threshold at which radiation levels induce changes in germ
cells?
Michael Ragland |
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Posted: Mon Feb 05, 2007 6:55 am |
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On Feb 4, 12:18�pm, "g" <gillaw...@earthlink.net> wrote:
Quote: Ragland,
I have an issue with the gross inconsistency of the MANY DIVERSE
rationales that have been tendered by many "experts" each speaking as though
from a cloud above -- if not Mt. Olympus, then certainly -- above the heads
of the ignorant masses of non-experts.
By 1900 there was a wide concensus among many fields of scientific inquiry
and speculation that there was a fundamental flaw in Darwin's concept of
natural selection, which was the SAME flaw in Lamarck's concept of
transmission of acquired characteristics; which was the SAME flaw in Herbert
Spencer's notion of "survival of the fittest," which... you get the idea...
was:
NONE OF THEM HAD COME UP WITH THE MECHANISM OR MECHANISMS PER
SE.
Ragland: Mechanism was natural selection.
Quote:
You and I know that Darwin kept REVISING his "Origin of the Species" in an
effort to "adapt" it to the objections of his peers. And historians who
have read the eleven or so REVISIONS have observed that, with each and every
rewrite his ideas became more, and more and more and more... guess what...
LAMARCKIAN.
Ragland: Not that I'm aware of.
Quote:
When Mendel's work got resurrected (roughly a half century after it first
came out), as a result of its being perceived by an increasing number of
theorists and critics to offer the missing "mechanism," that (if I've got it
right from my reading) was what enabled the New Darwinian Synthesis (also
called Neo-Darwinism). And some historians (if I've got this right)
indicate that up to then there was a wide split between the preference among
many leading biologists for the classical Darwinian view of "natural
selection" and the paleontologists' preference for a more Lamarckian view.
Ragland: Darwin came up with the mechanism which was natural
selection; Mendel came up with the genetics underlying it.
Quote: Putting it very succinctly (hence in risk of distortion by simplistication)
paleontologists and biologists had a new synthesis which both could see some
possible sense in.
Ragland: Okay.
Quote: Today, if we were to say that *THE MECHANISM WHEREBY NATURAL SELECTION
TRANSPIRES* is clear and present and of a sufficient degree of detailed
verification to be termed a "law" (in the scientific sense) that would be AT
VERY BEST premature... and, at WORST, it would be presumptious and could
turn out to be untenable somewhere downstream from today.
Ragland: I remember your earlier posts which were of Intelligent
Design persuation. As far as I'm concerned Darwin has not been
refuted.
Quote: This old layman has said it before and shall say it again, "Science is NOT
dogma. And deciples of a dogma, no matter how many experts might subscribe
to it, is not "top rate" science.
Ragland: Well I admit it seems dogmatic to state I'm convinced a
nuclear bomb will be detonated on a civilian/military location but
that's an opinion and doesn't have anything to do per se with
science..except that such nuclear science and weapons exist. As you
know there is not top rate science on s.b.e. There are some folks who
I think are scientific amateurs on here and even a few professionals.
I belong in neither category. So why am I here? Because the moderator
is flexible enough to include a wide variety on s.b.e. as long as it
has some tangible refererence to evolutionary biology.
Quote:
The angrier any entrenched advocate gets upon being accused of bias, the
more this old layman is reminded of the saying among political analysits
that, "When they say it's not about the money... it's about the money." I
use that analogy not because money is at issue (at least not in every
instance) but because certain GROUP CONSENSUSES as to the claiming of one
school of thought asserting their favorite presumptions against members of
members of another veritable cult of opinion, impress this old coot as more
of a "shouting match" and less of an actual search for answers... which is
what I would guess that "top rate" science should be about. And the
comparison is that when someone says it's not about a grouping of members of
a common opinion, that very well might be EXACTLY what it is about.
Ragland: Although you haven't addressed the subject of my post I can
assure you I believe a nuclear bomb will be detonated on a civilian
population somewhere down the road and there is a good chance it could
be the U.S. This is not the fare most like to think about.
Quote:
What ever happened to "I don't know.. but I'll tell you what I THINK," and
without opponents trying to enshrine their "opinion" in an ivory ego temple,
and put it on a pedestal.
Ragland: I'm going by what I've read and the current state of world
affairs and international terrorism.
Quote: If it were simple, obvious, and confirmed in minute detail, then there would
not BE any debate. And a many a person would not have to be called "stupid"
or "intransigent" or some such derogatory nomenclature for not bowing his
head in abject subjection.
Ragland: Some things can be "confirmed" before they actually "happen".
For example, even if the world adopted standards and enforced them to
limit global warming..global warming would still occur. It's not about
preventing global warming but mitigating it. This may be more
scientific than "predicting" another atom bomb will be detonated on a
civilian population but in a way I'm using the same principle.
Quote: If someone is going to point to a human and tell me that natural selection
by way of selfish genes made him smart enough to out-survive other critters,
then that person should not mind my asking, why the same did not happen to,
say, opossums. I read in a publication for game biologists that the very
most essential characteristic of Opossum Virginialis' which most accounts
for its adaptation to multiple geographical areas and invironments is the
fact that it is too stupid to get into habitat and food source ruts. More
specifically, the article informs that the cerebral cavity of a Virginia
Opossum, by comparison to other species indicates that it is "playing with
only about two-thirds of a deck."
Ragland: LOL. I wouldn't know about that. Something is serving the
Virginia Opossum well.
Quote: So what have we here. Smart out-survives dumb for humans; but dumb
out-survives smart for opossums.
Ragland: Each species operates by natural selection but each species
has its niche whether it be a fly, mosquito, roach, etc.
Quote:
Oh, the rationalizing might go, I'm not looking at the WHOLE picture. What
works for an opossum works for the niche or niches they fill, but does not
work for the niche or niches humans fill. Get the picture. If one STARTS
OUT with the presumption that natural selection works because of
competition, then the way you PROVE that is by coming up with a
rationalization for why hot is cold and black is white and smart pays when
it pays and dumb pays when it pays...
Ragland: I'm not a scientist so you're barking up the wrong tree with
me. It seems your playing semantics.
Quote: If a scientist speaks of gradualism, and points to many species that have
changed gradually, and cites that to be a product of mutations, even during
times when geography, that is fine so far as it goes. But let him NOT OMIT
telling me how rhinoceroses were, by comparison, less vulnerable to
gradualism.
Ragland: I once thought sharks were an evolutionary dead species; the
apparent fact they've not changed much in their basic form for
millions of years. Then I read sharks include many species and there
has been evolution of the species. No one can doubt there hasn't been
evolution of sharks.
Quote: I'll stop. There are far too many rationalizations built upon
rationalizations built upon rationalizations for this poor old man to keep
up with... except to observe that as gaps appear in one's hypothesization,
if he is totally committed to it, all that is necessary is to beg the
presumption and gerrymander an explanation as to how it applies to the
"seeming" exception.
Ragland: I don't think there are any gaps in my hypothesization a
nuclear bomb(s) will be detonated on civilian population(s) in the
future. The only gap is between now and when the event happens and
during that interval (which is occuring as we speak) developments are
already occurring which help make my prediction likely. I don't think
anybody can deal with a catastrophe until it happens so it does no
good to think about it except to try to be "mentally prepared" (if
such a thing is possible) for the worse to possibly occur.
> g |
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| Kevin Wayne Williams |
Posted: Tue Feb 06, 2007 8:51 am |
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RAGLANDMYCOOL@AOL.COM wrote:
Quote: Hey I just watched the Illusionist. I'm happy. Seriously though what
would be the limited effects on the ecology and biology if a few
nuclear bombs were detonated on populations? Would we just see alot of
radiation death and cancers? What would be the effects on the
worldwide climate?
I think we tried that experiment in August, 1945. The answer was "not
all that much on a global scale, terrifyingly devastating on a local scale."
KWW |
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| dhoyt |
Posted: Tue Feb 06, 2007 8:51 am |
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Quote:
Genomic instability posited the worse case scenario and no one has
responded. I find it hard to believe no germ cell damage was done to
the Japanese, Marshallese and victims of Cherynobyl. Are germ cells
really that robust? Have any experiments been done on animals and is
there a threshold at which radiation levels induce changes in germ
cells?
Michael Ragland
Take a look at: The effects of inbreeding on Japanese children [by]
William J. Schull and James V. Neel published in 1965.
Neel and Schull were with the Atomic Bomb Casualty Commission, which,
if I remember correctly, was formed right after the war to study the
effects of the bomb on the Japanese. My memory of this is pretty
sketchy, but I think they determined that there were very few
detectable mutations affecting viability among the children of bomb
survivors. (The strategy used was the compare the mortality of
children of consanguineous marriages with those of outbred marriages
among the bomb survivors in Hiroshima.) |
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| Guest |
Posted: Wed Feb 07, 2007 8:54 am |
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On Feb 6, 10:51�am, "dhoyt" <Dale.H...@gmail.com> wrote:
Quote: Genomic instability posited the worse case scenario and no one has
responded. I find it hard to believe no germ cell damage was done to
the Japanese, Marshallese and victims of Cherynobyl. Are germ cells
really that robust? Have any experiments been done on animals and is
there a threshold at which radiation levels induce changes in germ
cells?
Michael Ragland
Take a look at: The effects of inbreeding on Japanese children [by]
William J. Schull and James V. Neel published in 1965.
Neel and Schull were with the Atomic Bomb Casualty Commission, which,
if I remember correctly, was formed right after the war to study the
effects of the bomb on the Japanese. My memory of this is pretty
sketchy, but I think they determined that there were very few
detectable mutations affecting viability among the children of bomb
survivors. (The strategy used was the compare the mortality of
children of consanguineous marriages with those of outbred marriages
among the bomb survivors in Hiroshima.)
Ragland:
Apparently Chernobyl had alot more radiation than the atomic bombs
dropped on Japan. Yes, I read about the Atomic Bomb Casualty
Commission and it did determine very few detectable mutations
affecting viability among childen of bomb survivors. I find that hard
to accept. Here is what I read on Chernobyl:
GENETIC EFFECTS IN GERM CELLS
--------------------------------------------------------------------------------
National genetic monitoring in Belarus was developed by Prof. Lazyuk
G. and is functioning since 1979. The Belarusan monitoring can be
compared with the monitoring of Eurocat and International
Clearinghouse registers by the list of congenital developmental
malformations of strict control (anencephalia, meningoceles, cleft lip
and/or cleft palate, polydactylia, reduction defect of limbs, atresias
of esophagus and anus, Down's syndrome and, separately, the group of
multiple malformations) and by the method of their record-keeping.
Research by Lazyuk (1996) 27 according to the programme of Belarusan
national genetic monitoring has revealed that "The frequency of
Mandatory Registered Congenital Malformations has increased
significantly since 1986 in all the regions of Belarus, being most
pronounced in embryos, foetuses, and neonates from the areas with
137Cs contamination of 15 Ci/Km2 (555 kBq/m2). The observed increase
in the congenital malformation frequency in neonates considerably
exceeds the predictions made by the International Commission on
Radiological Protection" 28 .
As seen from the Table 4 an increase in the number of children with
congenital and hereditary malformations in the so-called clean regions
made up 24%, in the regions with 137Cs contamination density from 1 to
5 Ci/km2 did 30% and in the areas with contamination density of 15 Ci/
km2 and above made up 83%.
Year of observation Contamination zones Control group
1-5 Ci/km2 >15 Ci/km2
1982 5.74 3.06 5.62
1983 3.96 3.58 4.52
1984 4.32 3.94 4.17
1985 4.46 4.76 4.58
1982-1985 4.61 3.87 4.72
1987 5.54 8.14 5.94
1988 4.62 8.61 5.25
1989 6.32 6.50 5.80
1990 7.98 6.00 6.76
1991 5.65 4.88 5.52
1992 6.22 7.77 5.89
1987-1992 6.01* 7.09* 5.85*
Coefficient of increase 1.3 1.8 1.2
Table 4. Frequencies (per 1000 births) of congenital developmental
malformations (CDM) of strict control in 3 zones of Belarus
(1982-1992)
* P<0.05 28
The data of official statistics (Table 5) on recording infants with
congenital malformations (CM) in obstetric institutions of the whole
republic show a great increase in CM frequency (from 12.5 per 1000
infants in 1985 to 17.7 per 1000 infants in 1994 28 . However, if one
takes into consideration the number of pregnancies that were aborted
due to genetic indications (above 1500 pregnancies over the period of
1991-1994), the frequency of embryonal developmental disturbances
doesn't prove to be stabilised. It proceeds to increase (from 18.2 in
1992 to 22.4 in 1994).
Year Absolute number
of CDM Frequency per
1000 births
1985 2101 12.5
1986 2273 13.2
1987 2262 13.8
1988 2276 13.9
1989 2273 14.8
1990 2395 16.8
1991 2146 (261)* 16.2 (18.20)**
1992 2180 (367)* 17.0 (19.9)**
1993 2009 (400)* 17.0 (20.4)**
1994 1968 (523)* 17.7 (22.4)**
Table 5. Absolute numbers and congenital developmental malformation
(CDM) frequency in children in Belarus (The data of official
statistics )
* is the number of abortions due to genetic indications;
** is the total CDM frequency (the data of the Research Institute for
Congenital and Hereditary Diseases at the Ministry of Public Health of
the Republic of Belarus).
Lazyuk G. has compared mean doses, i.e. the sum of the effective
equivalent doses of external and internal irradiation for the
settlements were the parents lived with the frequency of congenital
developmental malformations in their children (Table 6) 27 . No direct
relationship between the frequency of congenital developmental
malformations and the dose taken by one or both parents before fetus
conception was observed. It should be noted, however, that the study
on the function of individual dose distribution for the population in
radiocontaminated areas showed that individual doses can be 5-6 times
as high as the mean dose values 4 .
Dose taken by puerperas (1986-1988) CDM frequency per 1000 births
(1987-1989)
0.8-1.4 7.02
1.4-2.3 8.67
2.4-8.14 8.14
Table 6. Frequency of congenital developmental malformations (CDM) in
Cs-137 contamination zone (from: 27 )
Taking into consideration the absence of significant correlation
between the frequency of congenital developmental malformations and
the Chernobyl dose, as well as rise in developmental malformations in
"clean" regions Lazyuk G. supposes the given data, in particular a
great increase in malformations of multifactorial origin, indicate
that the increase in embryonal development disturbances in the
population of Belarus is caused not only and, possibly, not so much by
ionising radiation, as by additional factors. Such additional factors
can be the following: inferior diet, chemical environmental
pollutants, alcoholization of reproductive age population and many
others.
However interpretation of sharp increase in developmental
malformations of strict control after 1986 and annual rise in all
recorded developmental malformations should be quite different, in my
opinion. The following aspects should be taken into account:
The so-called "clean" regions in Belarus are also radiocontaminated.
The myth on clean region greatly affects the researchers.
The forms of dose-effect relationships in the range of low doses of
prolonged chronic irradiation remain uncertain. There is evidence for
the existence of plateau phenomenon on dose curves. Therefore in the
range of low doses a monotonous rise in the frequency of congenital
developmental malformations with the dose increase might not be.
The type of nourishment for the whole population in Belarus is
practically similar though in 1986-1989 the attempts were made to
improve nourishment of people in the most contaminated regions.
The amount of chemical pollutants was considerably reduced due to
crisis in economy and annual rise in embryonal developmental
malformations is still observed.
The above stated, with good reason, makes it possible to regard an
unquestionable fact of a dramatic increase in congenital developmental
malformations as obvious consequence of the Chernobyl irradiation.
Discrepancy between data of Lazyuk 27 and those for children whose
parents had suffered from atomic bombardments in Japan seemed to be
caused by different conditions of radiation as a result of the
Chernobyl disaster and atomic explosions.
The joint research work of English, Russian and Belarusan
investigators 29 on the frequency of mutations in children whose both
parents constantly lived in the radiocontaminated Mogilev Region of
Belarus since the instant of the catastrophe is of great interest. The
range of area contamination was from 1 to 15 Ci/km2. An accurate dose
taken by the parents was unknown. The 137Cs contamination level of the
area, however, was a satisfactory indicator for moderate collective
radiation dose. The children born in February - September 1994 in 79
families formed the group under examination. Since the whole Belarus
is radiocontaminated, the children from 105 families of the Great
Britain formed the control group. The frequency of mutations in
minisattelite loci of the children from Mogilev Region turned out to
be increased twice, the total mutation number in the more contaminated
regions was 1.5 time as much as in the less contaminated ones. So, the
mutation frequency was shown to be correlated with the caesium
contamination level of the area.
This research work presented statistically significant data of two-
fold increase in the mutation frequency in germ cells of irradiated
parents. It should be noted that it is an unexpectedly high frequency
of mutability for mutations under the influence of radiation. The
value of a double dose for mutations in human germ cells resulting in
serious consequences for progeny health makes up 1 Gy 30 .
What is the dose taken by the people in Mogilev Region over the years
1986-1994? Its accurate value is unknown. However, according to the
assessment made in Belarus 2 an individual equivalent dose due to
external and internal irradiation is no less than 5 mSv per year (0.5
rem). An accumulated dose for 9 years achieves about 45 mSv or 4.5
rem. This is a very small dose in comparison with the value of the
double dose for human germ cells equal to 1 Gy.
The authors admit that either the estimates of the dose taken are
rather reduced or low doses of chronic irradiation are much more
effective inductors of mutations than high doses of acute irradiation.
However reduced the estimates of the taken doses were, they,
nevertheless, will be much lower than the accepted value of the double
dose. For a long time I am developing an idea of far higher efficiency
of chronic combined external and internal irradiation induced by the
radionuclide effect than acute or prolonged irradiation 31 32 .
A significant gain in the frequency of congenital and hereditary
pathology in children of the first irradiated generation as well as an
increased mutation frequency in germ cells 29 at low effective
equivalent doses received by their parents (0.8-5.2 cSv according to
the data of Lazyuk et al., 1996 28 ) indicates a mutagenic effect of
low doses of Chernobyl radiation.
There are forcible grounds for supposition that the value of a double
dose calculated on the basis of the data obtained for high radiation
doses is much higher than a double dose calculated by genetic effects
of low doses. Thus, when estimating a genetic risk of the Chernobyl
disaster, one should not base oneself upon the data obtained for
Japan.
Long-term investigations T. Nomura 33 34 35 in mice have shown
that:
mutations resulting in phenotypic anomalies (transplacental heritable
anomalies) emerge in germ cells under the influence of radiation
occurrence frequency of such mutations is 4-40 times as high as that
of other types of mutations;
sensitivity patterns of germ cells of mice and man to emergence of
heritable phenotypic anomalies according to Nomura's data are
similar.
Taking into account the above-stated points, increased
radiosensitivity of subsequent mammal generations to radionuclide
mutagenic effect illustrated by us 31 36 and some other aspects, I
think that for Chernobyl conditions (constant irradiation of a number
of generations) an increased frequency of hereditary defects in
children will remain in the present irradiated generation and after
1996, but it will increase in subsequent generations till it reaches
an equilibrium state 32 .
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GENETIC EFFECTS IN SOMATIC CELLS
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Study on dynamics of the mutation process in bank vole populations
inhabiting radiocontaminated regions of Belarus has shown that over
the period of 1986-1991, i.e. within some generations (12-1 in bone
marrow cells of animals were observed increased levels (in comparison
with pre-accident levels) of chromosome aberrations and genome
mutations (polyploidy) which occur in every generation de novo 32 .
The frequencies of genome mutations gradually and considerably
increased up to 1991 in the populations at all stations studied
reaching 14-15% in heavily radiocontaminated regions 31 . We have also
revealed an increased radiosensitivity of hereditary structures of
bank vole somatic cells of subsequent generations (animals of
1989-1991) in comparison with the previous generations (animals of
1986-1988) to the mutagenic influence of Chernobyl fall-out 31 . Our
and other research works show that chronic irradiation of various
animal species inhabiting radiocontaminated areas gives measurable
cytogenetic effects in somatic cells at very low levels of absorbed
doses (according to Cristaldi et al., 1991 37 for bank vole in Sweden
- 4-40x10-6 Gy per cell cycle).
Numerous data have shown that increased frequencies of cytogenetic
damages are characteristic, during some years, for blood cells of
people living in the radiocontaminated territories Thus, it was
revealed that existence of increased mutability of somatic cells is
peculiar for a long time to mammals and people exposed to chronic
radiation and receiving low dose loads. Extrapolation does not predict
such results.
Genetic radiosensitivity of mammals and man is known to be quite
close. Taking into account the above-stated and considering increased
radiosensitivity of animals of subsequent generations, one can assume
that an increased frequency of different type cytogenetic damages in
somatic cells of people living in radiocontaminated regions will
remain for quite a long time after 1996. Since chromosome aberrations
are a prognostic test, the presence of increased frequencies and other
types of mutations (gene, viability mutations etc.) should be expected
32 .
Consequences of such a permanently increased level of somatic cell
mutability for viability of living objects are considered below.
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HEALTH STATE OF THE PRESENT IRRADIATED GENERATION
--------------------------------------------------------------------------------
Epidemiological investigations have shown that in after-accident
period a steady increase in overall morbidity of children, pregnant
women and women of reproductive age as well as of the whole population
is characteristic of Belarus population living in radiocontaminated
regions. According to the data of Belarusan National Register on the
contaminated regions overall morbidity indices are higher than average
republican data. A gain in diseases of thyroid gland, circulatory
system, cardiovascular system (including cardial ischemia) liver and
pancreas is particularly pronounced. There is emerged the tendency
towards a rise in infant death rate. An increase in the incidence of
diabetes in liquidators was observed, the maximal rise being recorded
in the age group of 30-39 years 3 .
There are different points of view on reasons of increased morbidity
of people exposed to additional chronic radiation.
An increased level of cytogenetic damages in somatic cells was
observed in people living in radiocontaminated areas. The influence of
an increased frequency of different type mutation in somatic cells on
people's health is not found out for the present.
However now more information on the contribution of somatic cell
mutations in occurrence of diseases such as atherosclerosis, heart
diseases, diabetes, emphysema etc. is accumulated.
It allows us to propose an idea on the relation of increased morbidity
and reduced steadiness of people to the influence of any stress
factors with increased mutability of their somatic cells. In such
sense additional irradiation of people in radiocontaminated areas is a
factor promoting their increased sensitivity to any unfavourable
affects.
So, I think that an increased sickness rate of the population living
in radiocontaminated areas is a consequence of chronic low-dose
radiation 32 .
Information accumulated over 1986-1997 allows prediction of the
existence of a serious radiation risk for the population living in the
contaminated areas. |
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| Alan Meyer |
Posted: Wed Feb 07, 2007 8:54 am |
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On Feb 4, 3:19 pm, "g" <gillaw...@earthlink.net> wrote:
Quote: ...
How can random mutations come up with a linear progression from four toes to
a hoof in front and three toes to a hoof in the back? When we think long
and hard about it, what were the odds of a whole SERIES of mutations coming
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